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Page 1
Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations.
Yuan W, Stawiski E, Janakiraman V, Chan E, Durinck S, Edgar KA, Kljavin NM, Rivers CS, Gnad F, Roose-Girma M, Haverty PM, Fedorowicz G, Heldens S, Soriano RH, Zhang Z, Wallin JJ, Johnson L, Merchant M, Modrusan Z, Stern HM, Seshagiri S. Yuan W, et al. Among authors: seshagiri s. Oncogene. 2013 Jan 17;32(3):318-26. doi: 10.1038/onc.2012.53. Epub 2012 Feb 27. Oncogene. 2013. PMID: 22370636 Free PMC article.
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib.
Eberhard DA, Johnson BE, Amler LC, Goddard AD, Heldens SL, Herbst RS, Ince WL, Jänne PA, Januario T, Johnson DH, Klein P, Miller VA, Ostland MA, Ramies DA, Sebisanovic D, Stinson JA, Zhang YR, Seshagiri S, Hillan KJ. Eberhard DA, et al. Among authors: seshagiri s. J Clin Oncol. 2005 Sep 1;23(25):5900-9. doi: 10.1200/JCO.2005.02.857. Epub 2005 Jul 25. J Clin Oncol. 2005. PMID: 16043828 Clinical Trial.
Oncogenic BRAF is required for tumor growth and maintenance in melanoma models.
Hoeflich KP, Gray DC, Eby MT, Tien JY, Wong L, Bower J, Gogineni A, Zha J, Cole MJ, Stern HM, Murray LJ, Davis DP, Seshagiri S. Hoeflich KP, et al. Among authors: seshagiri s. Cancer Res. 2006 Jan 15;66(2):999-1006. doi: 10.1158/0008-5472.CAN-05-2720. Cancer Res. 2006. PMID: 16424035
Regulation of ERK3/MAPK6 expression by BRAF.
Hoeflich KP, Eby MT, Forrest WF, Gray DC, Tien JY, Stern HM, Murray LJ, Davis DP, Modrusan Z, Seshagiri S. Hoeflich KP, et al. Among authors: seshagiri s. Int J Oncol. 2006 Oct;29(4):839-49. Int J Oncol. 2006. PMID: 16964379
Distinguishing cancer-associated missense mutations from common polymorphisms.
Kaminker JS, Zhang Y, Waugh A, Haverty PM, Peters B, Sebisanovic D, Stinson J, Forrest WF, Bazan JF, Seshagiri S, Zhang Z. Kaminker JS, et al. Among authors: seshagiri s. Cancer Res. 2007 Jan 15;67(2):465-73. doi: 10.1158/0008-5472.CAN-06-1736. Cancer Res. 2007. PMID: 17234753
pHUSH: a single vector system for conditional gene expression.
Gray DC, Hoeflich KP, Peng L, Gu Z, Gogineni A, Murray LJ, Eby M, Kljavin N, Seshagiri S, Cole MJ, Davis DP. Gray DC, et al. Among authors: seshagiri s. BMC Biotechnol. 2007 Sep 26;7:61. doi: 10.1186/1472-6750-7-61. BMC Biotechnol. 2007. PMID: 17897455 Free PMC article.
118 results