Hou JQ - Search Results

1

2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling.

Li Z, Wang B, Hou JQ, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS. Li Z, et al. Among authors: hou jq. J Enzyme Inhib Med Chem. 2013 Jun;28(3):583-92. doi: 10.3109/14756366.2012.663363. Epub 2012 Mar 1. J Enzyme Inhib Med Chem. 2013. PMID: 22380775 Free article.

2

Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.

Pan L, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS. Pan L, et al. Among authors: hou jq. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3790-3. doi: 10.1016/j.bmcl.2008.05.039. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18524585

3

9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.

Ma Y, Ou TM, Hou JQ, Lu YJ, Tan JH, Gu LQ, Huang ZS. Ma Y, et al. Among authors: hou jq. Bioorg Med Chem. 2008 Aug 15;16(16):7582-91. doi: 10.1016/j.bmc.2008.07.029. Epub 2008 Jul 18. Bioorg Med Chem. 2008. PMID: 18674916

4

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ. Lu YJ, et al. Among authors: hou jq. J Med Chem. 2008 Oct 23;51(20):6381-92. doi: 10.1021/jm800497p. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821749

5

Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.

Tan JH, Ou TM, Hou JQ, Lu YJ, Huang SL, Luo HB, Wu JY, Huang ZS, Wong KY, Gu LQ. Tan JH, et al. Among authors: hou jq. J Med Chem. 2009 May 14;52(9):2825-35. doi: 10.1021/jm801600m. J Med Chem. 2009. PMID: 19354252

6

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.

Ma Y, Ou TM, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS. Ma Y, et al. Among authors: hou jq. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3414-7. doi: 10.1016/j.bmcl.2009.05.030. Epub 2009 May 14. Bioorg Med Chem Lett. 2009. PMID: 19477640

7

Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors.

Wang B, Mai YC, Li Y, Hou JQ, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS. Wang B, et al. Among authors: hou jq. Eur J Med Chem. 2010 Apr;45(4):1415-23. doi: 10.1016/j.ejmech.2009.12.044. Epub 2010 Jan 4. Eur J Med Chem. 2010. PMID: 20079560

8

Investigation on fragmentation pathways of rutaecarpine and its two derivatives using electrospray ionization ion-trap time-of-flight tandem mass spectrometry.

Wang B, Chu WY, Li Z, Hou JQ, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS. Wang B, et al. Among authors: hou jq. Rapid Commun Mass Spectrom. 2010 Sep;24(18):2781-6. doi: 10.1002/rcm.4697. Rapid Commun Mass Spectrom. 2010. PMID: 20814986 No abstract available.

9

New insights into the structures of ligand-quadruplex complexes from molecular dynamics simulations.

Hou JQ, Chen SB, Tan JH, Ou TM, Luo HB, Li D, Xu J, Gu LQ, Huang ZS. Hou JQ, et al. J Phys Chem B. 2010 Nov 25;114(46):15301-10. doi: 10.1021/jp106683n. Epub 2010 Nov 4. J Phys Chem B. 2010. PMID: 21049896

10

Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex.

Xu W, Tan JH, Chen SB, Hou JQ, Li D, Huang ZS, Gu LQ. Xu W, et al. Among authors: hou jq. Biochem Biophys Res Commun. 2011 Mar 18;406(3):454-8. doi: 10.1016/j.bbrc.2011.02.070. Epub 2011 Feb 17. Biochem Biophys Res Commun. 2011. PMID: 21333628

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