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Phase I dose-escalation study of vinflunine hard capsules administered twice a day for 2 consecutive days every week in patients with advanced/metastatic solid tumors.
Calvo E, Vermorken JB, Hiret S, Rodon J, Cortes J, Senellart H, Van den Brande J, Dyck J, Pétain A, Ferre P, Bennouna J. Calvo E, et al. Among authors: petain a. Cancer Chemother Pharmacol. 2012 Jun;69(6):1467-75. doi: 10.1007/s00280-012-1856-4. Epub 2012 Mar 1. Cancer Chemother Pharmacol. 2012. PMID: 22382883 Clinical Trial.
Phase I Clinical Pharmacology Study of F14512, a New Polyamine-Vectorized Anticancer Drug, in Naturally Occurring Canine Lymphoma.
Tierny D, Serres F, Segaoula Z, Bemelmans I, Bouchaert E, Pétain A, Brel V, Couffin S, Marchal T, Nguyen L, Thuru X, Ferré P, Guilbaud N, Gomes B. Tierny D, et al. Among authors: petain a. Clin Cancer Res. 2015 Dec 1;21(23):5314-23. doi: 10.1158/1078-0432.CCR-14-3174. Epub 2015 Jul 13. Clin Cancer Res. 2015. PMID: 26169968 Clinical Trial.
A randomised, multicentre open-label phase II study to evaluate the efficacy, tolerability and pharmacokinetics of oral vinorelbine plus cisplatin versus intravenous vinorelbine plus cisplatin in Chinese patients with chemotherapy-naive unresectable or metastatic non-small cell lung cancer.
Yang Y, Chang J, Huang C, Zhang Y, Wang J, Shu Y, Burillon JP, Riggi M, Petain A, Ferre P, Liang Y, Zhang L. Yang Y, et al. Among authors: petain a. J Thorac Dis. 2019 Aug;11(8):3347-3359. doi: 10.21037/jtd.2019.08.22. J Thorac Dis. 2019. PMID: 31559038 Free PMC article.
Phase I dose-escalation study of F14512, a polyamine-vectorized topoisomerase II inhibitor, in patients with platinum-refractory or resistant ovarian cancer.
Leary A, Le Tourneau C, Varga A, Sablin MP, Gomez-Roca C, Guilbaud N, Petain A, Pavlyuk M, Delord JP. Leary A, et al. Among authors: petain a. Invest New Drugs. 2019 Aug;37(4):693-701. doi: 10.1007/s10637-018-0688-4. Epub 2018 Dec 14. Invest New Drugs. 2019. PMID: 30547316 Free PMC article. Clinical Trial.
Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma.
Boyé P, Floch F, Serres F, Segaoula Z, Hordeaux J, Pascal Q, Coste V, Courapied S, Bouchaert E, Rybicka A, Mazuy C, Marescaux L, Geeraert K, Fournel-Fleury C, Duhamel A, Machuron F, Ferré P, Pétain A, Guilbaud N, Tierny D, Gomes B. Boyé P, et al. Among authors: petain a. Oncotarget. 2020 Feb 18;11(7):671-686. doi: 10.18632/oncotarget.27461. eCollection 2020 Feb 18. Oncotarget. 2020. PMID: 32133044 Free PMC article.
Pharmacokinetic behavior and appraisal of intravenous busulfan dosing in infants and older children: the results of a population pharmacokinetic study from a large pediatric cohort undergoing hematopoietic stem-cell transplantation.
Paci A, Vassal G, Moshous D, Dalle JH, Bleyzac N, Neven B, Galambrun C, Kemmel V, Abdi ZD, Broutin S, Pétain A, Nguyen L. Paci A, et al. Among authors: petain a. Ther Drug Monit. 2012 Apr;34(2):198-208. doi: 10.1097/FTD.0b013e31824c2f60. Ther Drug Monit. 2012. PMID: 22406655
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