The NOD2-RICK complex signals from the plasma membrane.
Lécine P, Esmiol S, Métais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP, Ollendorff V.
Lécine P, et al. Among authors: mcdonald c.
J Biol Chem. 2007 May 18;282(20):15197-207. doi: 10.1074/jbc.M606242200. Epub 2007 Mar 13.
J Biol Chem. 2007.
PMID: 17355968
Free article.
Although NOD2 is usually described as a cytosolic receptor for MDP, the protein is also localized at the plasma membrane, and the 1007FS mutation delocalizes NOD2 to the cytoplasm (Barnich, N., Aguirre, J. E., Reinecker, H. C., Xavier, R., and Podolsky, D. K. (2005) J. Cel …
Although NOD2 is usually described as a cytosolic receptor for MDP, the protein is also localized at the plasma membrane, and the 1007FS mut …