Medina-Franco J - Search Results

1

Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity, and human cell toxicity.

Bionda N, Stawikowski M, Stawikowska R, Cudic M, López-Vallejo F, Treitl D, Medina-Franco J, Cudic P. Bionda N, et al. ChemMedChem. 2012 May;7(5):871-82. doi: 10.1002/cmdc.201200016. Epub 2012 Mar 5. ChemMedChem. 2012. PMID: 22392790 Free PMC article.

2

Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach.

Medina-Franco JL, López-Vallejo F, Kuck D, Lyko F. Medina-Franco JL, et al. Mol Divers. 2011 May;15(2):293-304. doi: 10.1007/s11030-010-9262-5. Epub 2010 Aug 10. Mol Divers. 2011. PMID: 20697809

3

Benzotriazoles and indazoles are scaffolds with biological activity against Entamoeba histolytica.

López-Vallejo F, Castillo R, Yépez-Mulia L, Medina-Franco JL. López-Vallejo F, et al. J Biomol Screen. 2011 Sep;16(8):862-8. doi: 10.1177/1087057111414902. Epub 2011 Aug 5. J Biomol Screen. 2011. PMID: 21821786

4

Expanding the medicinally relevant chemical space with compound libraries.

López-Vallejo F, Giulianotti MA, Houghten RA, Medina-Franco JL. López-Vallejo F, et al. Drug Discov Today. 2012 Jul;17(13-14):718-26. doi: 10.1016/j.drudis.2012.04.001. Epub 2012 Apr 10. Drug Discov Today. 2012. PMID: 22515962 Review.

5

Increased diversity of libraries from libraries: chemoinformatic analysis of bis-diazacyclic libraries.

López-Vallejo F, Nefzi A, Bender A, Owen JR, Nabney IT, Houghten RA, Medina-Franco JL. López-Vallejo F, et al. Chem Biol Drug Des. 2011 May;77(5):328-42. doi: 10.1111/j.1747-0285.2011.01100.x. Epub 2011 Mar 1. Chem Biol Drug Des. 2011. PMID: 21294850 Free PMC article.

6

Computational methods for the discovery of mood disorder therapies.

López-Vallejo F, Peppard TL, Medina-Franco JL, Martínez-Mayorga K. López-Vallejo F, et al. Expert Opin Drug Discov. 2011 Dec;6(12):1227-45. doi: 10.1517/17460441.2011.637106. Epub 2011 Nov 15. Expert Opin Drug Discov. 2011. PMID: 22647063

7

Integrating virtual screening and combinatorial chemistry for accelerated drug discovery.

López-Vallejo F, Caulfield T, Martínez-Mayorga K, Giulianotti MA, Nefzi A, Houghten RA, Medina-Franco JL. López-Vallejo F, et al. Comb Chem High Throughput Screen. 2011 Jul;14(6):475-87. doi: 10.2174/138620711795767866. Comb Chem High Throughput Screen. 2011. PMID: 21521151 Review.

8

Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.

Navarrete-Vázquez G, Morales-Vilchis MG, Estrada-Soto S, Ramírez-Espinosa JJ, Hidalgo-Figueroa S, Nava-Zuazo C, Tlahuext H, Leon-Rivera I, Medina-Franco JL, López-Vallejo F, Webster SP, Binnie M, Ortiz-Andrade R, Moreno-Diaz H. Navarrete-Vázquez G, et al. Eur J Med Chem. 2014 Mar 3;74:179-86. doi: 10.1016/j.ejmech.2013.12.042. Epub 2014 Jan 8. Eur J Med Chem. 2014. PMID: 24462849

9

Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.

Singh N, Dueñas-González A, Lyko F, Medina-Franco JL. Singh N, et al. ChemMedChem. 2009 May;4(5):792-9. doi: 10.1002/cmdc.200900017. ChemMedChem. 2009. PMID: 19322801

10

Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors.

Castellano S, Kuck D, Viviano M, Yoo J, López-Vallejo F, Conti P, Tamborini L, Pinto A, Medina-Franco JL, Sbardella G. Castellano S, et al. J Med Chem. 2011 Nov 10;54(21):7663-77. doi: 10.1021/jm2010404. Epub 2011 Oct 7. J Med Chem. 2011. PMID: 21958292

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