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Page 1
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis.
Akhmetshina A, Palumbo K, Dees C, Bergmann C, Venalis P, Zerr P, Horn A, Kireva T, Beyer C, Zwerina J, Schneider H, Sadowski A, Riener MO, MacDougald OA, Distler O, Schett G, Distler JH. Akhmetshina A, et al. Among authors: kireva t. Nat Commun. 2012 Mar 13;3:735. doi: 10.1038/ncomms1734. Nat Commun. 2012. PMID: 22415826 Free PMC article.
β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis.
Beyer C, Schramm A, Akhmetshina A, Dees C, Kireva T, Gelse K, Sonnylal S, de Crombrugghe B, Taketo MM, Distler O, Schett G, Distler JH. Beyer C, et al. Among authors: kireva t. Ann Rheum Dis. 2012 May;71(5):761-7. doi: 10.1136/annrheumdis-2011-200568. Epub 2012 Feb 10. Ann Rheum Dis. 2012. PMID: 22328737 Free PMC article.
Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.
Lin NY, Beyer C, Giessl A, Kireva T, Scholtysek C, Uderhardt S, Munoz LE, Dees C, Distler A, Wirtz S, Krönke G, Spencer B, Distler O, Schett G, Distler JH. Lin NY, et al. Among authors: kireva t. Ann Rheum Dis. 2013 May;72(5):761-8. doi: 10.1136/annrheumdis-2012-201671. Epub 2012 Sep 12. Ann Rheum Dis. 2013. PMID: 22975756
Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus.
Kiechl S, Wittmann J, Giaccari A, Knoflach M, Willeit P, Bozec A, Moschen AR, Muscogiuri G, Sorice GP, Kireva T, Summerer M, Wirtz S, Luther J, Mielenz D, Billmeier U, Egger G, Mayr A, Oberhollenzer F, Kronenberg F, Orthofer M, Penninger JM, Meigs JB, Bonora E, Tilg H, Willeit J, Schett G. Kiechl S, et al. Among authors: kireva t. Nat Med. 2013 Mar;19(3):358-63. doi: 10.1038/nm.3084. Epub 2013 Feb 10. Nat Med. 2013. PMID: 23396210
Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis.
Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J, Tagariello A, Onnerfjord P, Heinegård D, Schlötzer-Schrehardt U, Deutzmann R, von der Mark K, Stock M. Surmann-Schmitt C, et al. Among authors: kireva t. J Biol Chem. 2008 Mar 14;283(11):7082-93. doi: 10.1074/jbc.M702792200. Epub 2007 Dec 21. J Biol Chem. 2008. PMID: 18156182 Free article.