Helin K - Search Results

1

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.

Kristensen LH, Nielsen AL, Helgstrand C, Lees M, Cloos P, Kastrup JS, Helin K, Olsen L, Gajhede M. Kristensen LH, et al. Among authors: helin k. FEBS J. 2012 Jun;279(11):1905-14. doi: 10.1111/j.1742-4658.2012.08567.x. Epub 2012 May 2. FEBS J. 2012. PMID: 22420752 Free article.

2

Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription.

Christensen J, Cloos P, Toftegaard U, Klinkenberg D, Bracken AP, Trinh E, Heeran M, Di Stefano L, Helin K. Christensen J, et al. Among authors: helin k. Nucleic Acids Res. 2005 Sep 22;33(17):5458-70. doi: 10.1093/nar/gki855. Print 2005. Nucleic Acids Res. 2005. PMID: 16179649 Free PMC article.

3

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3.

Cloos PA, Christensen J, Agger K, Maiolica A, Rappsilber J, Antal T, Hansen KH, Helin K. Cloos PA, et al. Among authors: helin k. Nature. 2006 Jul 20;442(7100):307-11. doi: 10.1038/nature04837. Epub 2006 May 28. Nature. 2006. PMID: 16732293

4

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.

Christensen J, Agger K, Cloos PA, Pasini D, Rose S, Sennels L, Rappsilber J, Hansen KH, Salcini AE, Helin K. Christensen J, et al. Among authors: helin k. Cell. 2007 Mar 23;128(6):1063-76. doi: 10.1016/j.cell.2007.02.003. Epub 2007 Feb 22. Cell. 2007. PMID: 17320161 Free article.

5

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K. Agger K, et al. Among authors: helin k. Nature. 2007 Oct 11;449(7163):731-4. doi: 10.1038/nature06145. Epub 2007 Aug 22. Nature. 2007. PMID: 17713478

6

The emerging functions of histone demethylases.

Agger K, Christensen J, Cloos PA, Helin K. Agger K, et al. Among authors: helin k. Curr Opin Genet Dev. 2008 Apr;18(2):159-68. doi: 10.1016/j.gde.2007.12.003. Epub 2008 Feb 20. Curr Opin Genet Dev. 2008. PMID: 18281209 Review.

7

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.

Cloos PA, Christensen J, Agger K, Helin K. Cloos PA, et al. Among authors: helin k. Genes Dev. 2008 May 1;22(9):1115-40. doi: 10.1101/gad.1652908. Genes Dev. 2008. PMID: 18451103 Free PMC article. Review.

8

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D, Hansen KH, Christensen J, Agger K, Cloos PA, Helin K. Pasini D, et al. Among authors: helin k. Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008. Genes Dev. 2008. PMID: 18483221 Free PMC article.

9

Regulation of stem cell differentiation by histone methyltransferases and demethylases.

Pasini D, Bracken AP, Agger K, Christensen J, Hansen K, Cloos PA, Helin K. Pasini D, et al. Among authors: helin k. Cold Spring Harb Symp Quant Biol. 2008;73:253-63. doi: 10.1101/sqb.2008.73.009. Epub 2008 Nov 6. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19022750 Free article. Review.

10

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence.

Agger K, Cloos PA, Rudkjaer L, Williams K, Andersen G, Christensen J, Helin K. Agger K, et al. Among authors: helin k. Genes Dev. 2009 May 15;23(10):1171-6. doi: 10.1101/gad.510809. Genes Dev. 2009. PMID: 19451217 Free PMC article.

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