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Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.
Brettschneider J, Van Deerlin VM, Robinson JL, Kwong L, Lee EB, Ali YO, Safren N, Monteiro MJ, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina-Porcel L, Lee VM, Trojanowski JQ. Brettschneider J, et al. Among authors: kwong l. Acta Neuropathol. 2012 Jun;123(6):825-39. doi: 10.1007/s00401-012-0970-z. Epub 2012 Mar 18. Acta Neuropathol. 2012. PMID: 22426854 Free PMC article.
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Igaz LM, Kwong LK, Xu Y, Truax AC, Uryu K, Neumann M, Clark CM, Elman LB, Miller BL, Grossman M, McCluskey LF, Trojanowski JQ, Lee VM. Igaz LM, et al. Among authors: kwong lk. Am J Pathol. 2008 Jul;173(1):182-94. doi: 10.2353/ajpath.2008.080003. Epub 2008 Jun 5. Am J Pathol. 2008. PMID: 18535185 Free PMC article.
TDP-43 skeins show properties of amyloid in a subset of ALS cases.
Robinson JL, Geser F, Stieber A, Umoh M, Kwong LK, Van Deerlin VM, Lee VM, Trojanowski JQ. Robinson JL, et al. Among authors: kwong lk. Acta Neuropathol. 2013 Jan;125(1):121-31. doi: 10.1007/s00401-012-1055-8. Epub 2012 Nov 3. Acta Neuropathol. 2013. PMID: 23124365 Free PMC article.
341 results