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New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.
La Regina G, Sarkar T, Bai R, Edler MC, Saletti R, Coluccia A, Piscitelli F, Minelli L, Gatti V, Mazzoccoli C, Palermo V, Mazzoni C, Falcone C, Scovassi AI, Giansanti V, Campiglia P, Porta A, Maresca B, Hamel E, Brancale A, Novellino E, Silvestri R. La Regina G, et al. Among authors: piscitelli f. J Med Chem. 2009 Dec 10;52(23):7512-27. doi: 10.1021/jm900016t. J Med Chem. 2009. PMID: 19601594 Free PMC article.
Arylthioindoles: Promising compounds against cancer cell proliferation.
Giansanti V, Piscitelli F, Camboni T, Prosperi E, LA Regina G, Parks M, Silvestri R, Scovassi AI. Giansanti V, et al. Among authors: piscitelli f. Oncol Lett. 2010 Jan;1(1):109-112. doi: 10.3892/ol_00000020. Epub 2010 Jan 1. Oncol Lett. 2010. PMID: 22966266 Free PMC article.
Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.
La Regina G, Bai R, Rensen W, Coluccia A, Piscitelli F, Gatti V, Bolognesi A, Lavecchia A, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Mariani M, Santoni A, Brancale A, Ferlini C, Dondio G, Varasi M, Mercurio C, Hamel E, Lavia P, Novellino E, Silvestri R. La Regina G, et al. Among authors: piscitelli f. J Med Chem. 2011 Dec 22;54(24):8394-406. doi: 10.1021/jm2012886. Epub 2011 Nov 21. J Med Chem. 2011. PMID: 22044164 Free PMC article.
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
Piscitelli F, Coluccia A, Brancale A, La Regina G, Sansone A, Giordano C, Balzarini J, Maga G, Zanoli S, Samuele A, Cirilli R, La Torre F, Lavecchia A, Novellino E, Silvestri R. Piscitelli F, et al. J Med Chem. 2009 Apr 9;52(7):1922-34. doi: 10.1021/jm801470b. J Med Chem. 2009. PMID: 19281225
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
La Regina G, Edler MC, Brancale A, Kandil S, Coluccia A, Piscitelli F, Hamel E, De Martino G, Matesanz R, Díaz JF, Scovassi AI, Prosperi E, Lavecchia A, Novellino E, Artico M, Silvestri R. La Regina G, et al. Among authors: piscitelli f. J Med Chem. 2007 Jun 14;50(12):2865-74. doi: 10.1021/jm061479u. Epub 2007 May 12. J Med Chem. 2007. PMID: 17497841
220 results