Clarke R - Search Results

1

Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK).

Shajahan AN, Dobbin ZC, Hickman FE, Dakshanamurthy S, Clarke R. Shajahan AN, et al. Among authors: clarke r. J Biol Chem. 2012 May 18;287(21):17682-17692. doi: 10.1074/jbc.M111.304022. Epub 2012 Mar 20. J Biol Chem. 2012. PMID: 22433870 Free PMC article.

2

Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats.

Hilakivi-Clarke L, Olivo SE, Shajahan A, Khan G, Zhu Y, Zwart A, Cho E, Clarke R. Hilakivi-Clarke L, et al. Among authors: clarke r. J Nutr. 2005 Dec;135(12 Suppl):2946S-2952S. doi: 10.1093/jn/135.12.2946S. J Nutr. 2005. PMID: 16317153 Free article. Review.

3

Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity.

Shajahan AN, Wang A, Decker M, Minshall RD, Liu MC, Clarke R. Shajahan AN, et al. Among authors: clarke r. J Biol Chem. 2007 Feb 23;282(8):5934-43. doi: 10.1074/jbc.M608857200. Epub 2006 Dec 26. J Biol Chem. 2007. PMID: 17190831 Free article.

4

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

Gomez BP, Riggins RB, Shajahan AN, Klimach U, Wang A, Crawford AC, Zhu Y, Zwart A, Wang M, Clarke R. Gomez BP, et al. Among authors: clarke r. FASEB J. 2007 Dec;21(14):4013-27. doi: 10.1096/fj.06-7990com. Epub 2007 Jul 27. FASEB J. 2007. PMID: 17660348

5

Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells.

Clarke R, Shajahan AN, Riggins RB, Cho Y, Crawford A, Xuan J, Wang Y, Zwart A, Nehra R, Liu MC. Clarke R, et al. J Steroid Biochem Mol Biol. 2009 Mar;114(1-2):8-20. doi: 10.1016/j.jsbmb.2008.12.023. J Steroid Biochem Mol Biol. 2009. PMID: 19444933 Free PMC article.

6

The role of X-box binding protein-1 in tumorigenicity.

Shajahan AN, Riggins RB, Clarke R. Shajahan AN, et al. Among authors: clarke r. Drug News Perspect. 2009 Jun;22(5):241-6. doi: 10.1358/dnp.2009.22.5.1378631. Drug News Perspect. 2009. PMID: 19609461 Free PMC article. Review.

7

Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis.

Crawford AC, Riggins RB, Shajahan AN, Zwart A, Clarke R. Crawford AC, et al. Among authors: clarke r. PLoS One. 2010 Jan 6;5(1):e8604. doi: 10.1371/journal.pone.0008604. PLoS One. 2010. PMID: 20062536 Free PMC article.

8

BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells.

Nehra R, Riggins RB, Shajahan AN, Zwart A, Crawford AC, Clarke R. Nehra R, et al. Among authors: clarke r. FASEB J. 2010 Jun;24(6):2040-55. doi: 10.1096/fj.09-138305. Epub 2010 Feb 12. FASEB J. 2010. PMID: 20154269 Free PMC article.

9

IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis.

Ning Y, Riggins RB, Mulla JE, Chung H, Zwart A, Clarke R. Ning Y, et al. Among authors: clarke r. Mol Cancer Ther. 2010 May;9(5):1274-85. doi: 10.1158/1535-7163.MCT-09-1169. Mol Cancer Ther. 2010. PMID: 20457620 Free PMC article.

10

Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells.

Patacsil D, Osayi S, Tran AT, Saenz F, Yimer L, Shajahan AN, Gokhale PC, Verma M, Clarke R, Chauhan SC, Kumar D. Patacsil D, et al. Among authors: clarke r. Genes Nutr. 2012 Jan;7(1):83-9. doi: 10.1007/s12263-011-0242-x. Epub 2011 Aug 13. Genes Nutr. 2012. PMID: 21842182 Free PMC article.

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