Walsh DM - Search Results

1

The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain.

McDonald JM, Cairns NJ, Taylor-Reinwald L, Holtzman D, Walsh DM. McDonald JM, et al. Among authors: walsh dm. Brain Res. 2012 Apr 23;1450:138-47. doi: 10.1016/j.brainres.2012.02.041. Epub 2012 Feb 24. Brain Res. 2012. PMID: 22440675 Free PMC article.

2

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

Walsh DM, Klyubin I, Shankar GM, Townsend M, Fadeeva JV, Betts V, Podlisny MB, Cleary JP, Ashe KH, Rowan MJ, Selkoe DJ. Walsh DM, et al. Biochem Soc Trans. 2005 Nov;33(Pt 5):1087-90. doi: 10.1042/BST20051087. Biochem Soc Trans. 2005. PMID: 16246051 Review.

3

A beta oligomers - a decade of discovery.

Walsh DM, Selkoe DJ. Walsh DM, et al. J Neurochem. 2007 Jun;101(5):1172-84. doi: 10.1111/j.1471-4159.2006.04426.x. Epub 2007 Feb 5. J Neurochem. 2007. PMID: 17286590 Free article. Review.

4

The APP family of proteins: similarities and differences.

Walsh DM, Minogue AM, Sala Frigerio C, Fadeeva JV, Wasco W, Selkoe DJ. Walsh DM, et al. Biochem Soc Trans. 2007 Apr;35(Pt 2):416-20. doi: 10.1042/BST0350416. Biochem Soc Trans. 2007. PMID: 17371289

5

Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.

Farris W, Schütz SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM, Selkoe DJ. Farris W, et al. Among authors: walsh dm. Am J Pathol. 2007 Jul;171(1):241-51. doi: 10.2353/ajpath.2007.070105. Am J Pathol. 2007. PMID: 17591969 Free PMC article.

6

Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin.

Betts V, Leissring MA, Dolios G, Wang R, Selkoe DJ, Walsh DM. Betts V, et al. Among authors: walsh dm. Neurobiol Dis. 2008 Sep;31(3):442-50. doi: 10.1016/j.nbd.2008.06.001. Epub 2008 Jun 17. Neurobiol Dis. 2008. PMID: 18602473 Free PMC article.

7

Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo.

Hu NW, Smith IM, Walsh DM, Rowan MJ. Hu NW, et al. Among authors: walsh dm. Brain. 2008 Sep;131(Pt 9):2414-24. doi: 10.1093/brain/awn174. Epub 2008 Aug 4. Brain. 2008. PMID: 18678563

8

A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide.

Walsh DM, Thulin E, Minogue AM, Gustavsson N, Pang E, Teplow DB, Linse S. Walsh DM, et al. FEBS J. 2009 Mar;276(5):1266-81. doi: 10.1111/j.1742-4658.2008.06862.x. FEBS J. 2009. PMID: 19175671 Free PMC article.

9

gamma-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons.

Minogue AM, Stubbs AK, Frigerio CS, Boland B, Fadeeva JV, Tang J, Selkoe DJ, Walsh DM. Minogue AM, et al. Among authors: walsh dm. Brain Res. 2009 Mar 25;1262:89-99. doi: 10.1016/j.brainres.2009.01.008. Epub 2009 Jan 18. Brain Res. 2009. PMID: 19401174

10

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life.

Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM. Shankar GM, et al. Among authors: walsh dm. Neurobiol Dis. 2009 Nov;36(2):293-302. doi: 10.1016/j.nbd.2009.07.021. Epub 2009 Aug 4. Neurobiol Dis. 2009. PMID: 19660551 Free PMC article.

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