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Impaired suppression of fatty acid release by insulin is a strong predictor of reduced whole-body insulin-mediated glucose uptake and skeletal muscle insulin receptor activation.
Schleh MW, Ryan BJ, Ahn C, Ludzki AC, Van Pelt DW, Pitchford LM, Chugh OK, Luker AT, Luker KE, Samovski D, Abumrad NA, Burant CF, Horowitz JF. Schleh MW, et al. Among authors: van pelt dw. Acta Physiol (Oxf). 2025 Jan;241(1):e14249. doi: 10.1111/apha.14249. Epub 2024 Nov 1. Acta Physiol (Oxf). 2025. PMID: 39487600 Free PMC article.
Both moderate- and high-intensity exercise training increase intramyocellular lipid droplet abundance and modify myocellular distribution in adults with obesity.
Schleh MW, Ahn C, Ryan BJ, Chugh OK, Luker AT, Luker KE, Gillen JB, Ludzki AC, Van Pelt DW, Pitchford LM, Zhang T, Rode T, Howton SM, Burant CF, Horowitz JF. Schleh MW, et al. Among authors: van pelt dw. Am J Physiol Endocrinol Metab. 2023 Nov 1;325(5):E466-E479. doi: 10.1152/ajpendo.00093.2023. Epub 2023 Sep 20. Am J Physiol Endocrinol Metab. 2023. PMID: 37729021 Free PMC article.
Metabolic dysfunction in obesity is related to impaired suppression of fatty acid release from adipose tissue by insulin.
Schleh MW, Ryan BJ, Ahn C, Ludzki AC, Varshney P, Gillen JB, Van Pelt DW, Pitchford LM, Howton SM, Rode T, Chenevert TL, Hummel SL, Burant CF, Horowitz JF. Schleh MW, et al. Among authors: van pelt dw. Obesity (Silver Spring). 2023 May;31(5):1347-1361. doi: 10.1002/oby.23734. Epub 2023 Mar 29. Obesity (Silver Spring). 2023. PMID: 36988872 Free PMC article.
Temporal disruption of neuromuscular communication and muscle atrophy following noninvasive ACL injury in rats.
Hunt ER, Davi SM, Parise CN, Clark K, Van Pelt DW, Confides AL, Buckholts KA, Jacobs CA, Lattermann C, Dupont-Versteegden EE, Butterfield TA, Lepley LK. Hunt ER, et al. Among authors: van pelt dw. J Appl Physiol (1985). 2022 Jan 1;132(1):46-57. doi: 10.1152/japplphysiol.00070.2021. Epub 2021 Nov 11. J Appl Physiol (1985). 2022. PMID: 34762530 Free PMC article.
63 results