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Page 1
Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent.
Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: fujii y. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2803-6. doi: 10.1016/j.bmcl.2012.02.072. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22444677
Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent.
Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: fujii y. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2898-901. doi: 10.1016/j.bmcl.2012.02.050. Epub 2012 Feb 23. Bioorg Med Chem Lett. 2012. PMID: 22421019
CB 1/2 dual agonists with 3-carbamoyl 2-pyridone derivatives as antipruritics: reduction of CNS side effects by introducing polar functional groups.
Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: fujii y. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2894-7. doi: 10.1016/j.bmcl.2012.02.054. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22437111
Pyrrolidine inhibitors of human cytosolic phospholipase A(2).
Seno K, Okuno T, Nishi K, Murakami Y, Watanabe F, Matsuura T, Wada M, Fujii Y, Yamada M, Ogawa T, Okada T, Hashizume H, Kii M, Hara S, Hagishita S, Nakamoto S, Yamada K, Chikazawa Y, Ueno M, Teshirogi I, Ono T, Ohtani M. Seno K, et al. Among authors: fujii y. J Med Chem. 2000 Mar 23;43(6):1041-4. doi: 10.1021/jm9905155. J Med Chem. 2000. PMID: 10737736 No abstract available.
Discovery of clinical candidate Sivopixant (S-600918): Lead optimization of dioxotriazine derivatives as selective P2X3 receptor antagonists.
Kai H, Horiguchi T, Kameyma T, Onodera N, Itoh N, Fujii Y, Ichihashi Y, Hirai K, Shintani T, Nakamura K, Minami K, Kasai E, Yoneda S, Murakami Y, Ogawa H, Sekimoto R, Shinohara S, Yoshida O, Kurose N. Kai H, et al. Among authors: fujii y. Bioorg Med Chem Lett. 2021 Nov 15;52:128384. doi: 10.1016/j.bmcl.2021.128384. Epub 2021 Sep 26. Bioorg Med Chem Lett. 2021. PMID: 34587541 Free article.
Detection and analysis of Serpin and RP26 specific antibodies for monitoring Schistosoma haematobium transmission.
Kokubo-Tanaka M, Kildemoes AO, Chadeka EA, Cheruiyot BN, Moriyasu T, Sassa M, Nakamura R, Kikuchi M, Fujii Y, de Dood CJ, Corstjens PLAM, Kaneko S, Maruyama H, Njenga SM, de Vrueh R, Hokke CH, Hamano S. Kokubo-Tanaka M, et al. Among authors: fujii y. PLoS Negl Trop Dis. 2025 Jan 24;19(1):e0012813. doi: 10.1371/journal.pntd.0012813. eCollection 2025 Jan. PLoS Negl Trop Dis. 2025. PMID: 39854314
PI5P4K inhibitors: promising opportunities and challenges.
Takeuchi K, Nagase L, Kageyama S, Kanoh H, Oshima M, Ogawa-Iio A, Ikeda Y, Fujii Y, Kondo S, Osaka N, Masuda T, Ishihara T, Nakamura Y, Hirota Y, Sasaki T, Senda T, Sasaki AT. Takeuchi K, et al. Among authors: fujii y. FEBS J. 2025 Jan 19. doi: 10.1111/febs.17393. Online ahead of print. FEBS J. 2025. PMID: 39828902 Review.
4,567 results