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Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis.
Seizer P, Klingel K, Sauter M, Westermann D, Ochmann C, Schönberger T, Schleicher R, Stellos K, Schmidt EM, Borst O, Bigalke B, Kandolf R, Langer H, Gawaz M, May AE. Seizer P, et al. Among authors: kandolf r. J Mol Cell Cardiol. 2012 Jul;53(1):6-14. doi: 10.1016/j.yjmcc.2012.03.004. Epub 2012 Mar 15. J Mol Cell Cardiol. 2012. PMID: 22446162
Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion.
Seizer P, Ochmann C, Schönberger T, Zach S, Rose M, Borst O, Klingel K, Kandolf R, MacDonald HR, Nowak RA, Engelhardt S, Lang F, Gawaz M, May AE. Seizer P, et al. Among authors: kandolf r. Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1377-86. doi: 10.1161/ATVBAHA.111.225771. Epub 2011 Mar 24. Arterioscler Thromb Vasc Biol. 2011. PMID: 21441138 Free PMC article.
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Heinzmann D, Bangert A, Müller AM, von Ungern-Sternberg SN, Emschermann F, Schönberger T, Chatterjee M, Mack AF, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer HF, Katus H, Fischer G, May AE, Kaya Z, Seizer P. Heinzmann D, et al. Among authors: kandolf r. PLoS One. 2015 Apr 20;10(4):e0124606. doi: 10.1371/journal.pone.0124606. eCollection 2015. PLoS One. 2015. PMID: 25894208 Free PMC article.
315 results