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TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.
Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE. Liu A, et al. Among authors: puche ac. J Biol Chem. 2012 May 11;287(20):16132-45. doi: 10.1074/jbc.M111.310102. Epub 2012 Mar 23. J Biol Chem. 2012. PMID: 22447928 Free PMC article.
Expression of sialyltransferase activity on intact human neutrophils.
Rifat S, Kang TJ, Mann D, Zhang L, Puche AC, Stamatos NM, Goldblum SE, Brossmer R, Cross AS. Rifat S, et al. Among authors: puche ac. J Leukoc Biol. 2008 Oct;84(4):1075-81. doi: 10.1189/jlb.0706462. Epub 2008 Jul 29. J Leukoc Biol. 2008. PMID: 18664529 Free PMC article.
The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation.
Goldblum SE, Rai U, Tripathi A, Thakar M, De Leo L, Di Toro N, Not T, Ramachandran R, Puche AC, Hollenberg MD, Fasano A. Goldblum SE, et al. Among authors: puche ac. FASEB J. 2011 Jan;25(1):144-58. doi: 10.1096/fj.10-158972. Epub 2010 Sep 17. FASEB J. 2011. PMID: 20852064 Free PMC article.
NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.
Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE. Lillehoj EP, et al. Among authors: puche ac. J Biol Chem. 2012 Mar 9;287(11):8214-31. doi: 10.1074/jbc.M111.292888. Epub 2012 Jan 13. J Biol Chem. 2012. PMID: 22247545 Free PMC article.
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, Passaniti A, Goldblum SE. Cross AS, et al. Among authors: puche ac. J Biol Chem. 2012 May 4;287(19):15966-80. doi: 10.1074/jbc.M112.346817. Epub 2012 Mar 8. J Biol Chem. 2012. PMID: 22403397 Free PMC article.
Human airway epithelia express catalytically active NEU3 sialidase.
Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Sun W, Luzina IG, Webb TJ, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE. Lillehoj EP, et al. Among authors: puche ac. Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L876-86. doi: 10.1152/ajplung.00322.2013. Epub 2014 Mar 21. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24658138 Free PMC article.
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