Azoitei N - Search Results

1

Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.

Azoitei N, Hoffmann CM, Ellegast JM, Ball CR, Obermayer K, Gößele U, Koch B, Faber K, Genze F, Schrader M, Kestler HA, Döhner H, Chiosis G, Glimm H, Fröhling S, Scholl C. Azoitei N, et al. J Exp Med. 2012 Apr 9;209(4):697-711. doi: 10.1084/jem.20111910. Epub 2012 Mar 26. J Exp Med. 2012. PMID: 22451720 Free PMC article.

2

Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours.

Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T. Azoitei N, et al. Gut. 2010 Oct;59(10):1316-30. doi: 10.1136/gut.2009.206813. Epub 2010 Aug 23. Gut. 2010. PMID: 20732914

3

Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.

Azoitei N, Kleger A, Schoo N, Thal DR, Brunner C, Pusapati GV, Filatova A, Genze F, Möller P, Acker T, Kuefer R, Van Lint J, Baust H, Adler G, Seufferlein T. Azoitei N, et al. Neuro Oncol. 2011 Jul;13(7):710-24. doi: 10.1093/neuonc/nor084. Neuro Oncol. 2011. PMID: 21727210 Free PMC article.

4

HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization.

Azoitei N, Diepold K, Brunner C, Rouhi A, Genze F, Becher A, Kestler H, van Lint J, Chiosis G, Koren J 3rd, Fröhling S, Scholl C, Seufferlein T. Azoitei N, et al. Cancer Res. 2014 Dec 1;74(23):7125-36. doi: 10.1158/0008-5472.CAN-14-1017. Epub 2014 Oct 8. Cancer Res. 2014. PMID: 25297628 Free PMC article.

5

A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells.

Müller M, Schröer J, Azoitei N, Eiseler T, Bergmann W, Köhntop R, Lin Q, Costa IG, Zenke M, Genze F, Weidgang C, Seufferlein T, Liebau S, Kleger A. Müller M, et al. Among authors: azoitei n. Sci Rep. 2015 Jul 7;5:11742. doi: 10.1038/srep11742. Sci Rep. 2015. PMID: 26148697 Free PMC article.

6

PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation.

Azoitei N, Becher A, Steinestel K, Rouhi A, Diepold K, Genze F, Simmet T, Seufferlein T. Azoitei N, et al. Mol Cancer. 2016 Jan 6;15:3. doi: 10.1186/s12943-015-0490-2. Mol Cancer. 2016. PMID: 26739387 Free PMC article.

7

PRKD2: A two-pronged kinase crucial for the tumor-supporting activity of HSP90.

Azoitei N, Fröhling S, Scholl C, Seufferlein T. Azoitei N, et al. Mol Cell Oncol. 2015 Jan 7;2(2):e981444. doi: 10.4161/23723556.2014.981444. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308444 Free PMC article.

8

STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1α/VEGF signaling pathway.

Liu Y, Steinestel K, Rouhi A, Armacki M, Diepold K, Chiosis G, Simmet T, Seufferlein T, Azoitei N. Liu Y, et al. Among authors: azoitei n. Oncotarget. 2017 Aug 24;8(44):77474-77488. doi: 10.18632/oncotarget.20535. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100402 Free PMC article.

9

Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.

Armacki M, Trugenberger AK, Ellwanger AK, Eiseler T, Schwerdt C, Bettac L, Langgartner D, Azoitei N, Halbgebauer R, Groß R, Barth T, Lechel A, Walter BM, Kraus JM, Wiegreffe C, Grimm J, Scheffold A, Schneider MR, Peuker K, Zeißig S, Britsch S, Rose-John S, Vettorazzi S, Wolf E, Tannapfel A, Steinestel K, Reber SO, Walther P, Kestler HA, Radermacher P, Barth TF, Huber-Lang M, Kleger A, Seufferlein T. Armacki M, et al. Among authors: azoitei n. J Clin Invest. 2018 Nov 1;128(11):5056-5072. doi: 10.1172/JCI97912. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30320600 Free PMC article.

10

Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone.

Bekeschus S, Lippert M, Diepold K, Chiosis G, Seufferlein T, Azoitei N. Bekeschus S, et al. Among authors: azoitei n. Sci Rep. 2019 Mar 11;9(1):4112. doi: 10.1038/s41598-019-38580-0. Sci Rep. 2019. PMID: 30858416 Free PMC article.

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