Conlon DM - Search Results

1

Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.

Ai D, Baez JM, Jiang H, Conlon DM, Hernandez-Ono A, Frank-Kamenetsky M, Milstein S, Fitzgerald K, Murphy AJ, Woo CW, Strong A, Ginsberg HN, Tabas I, Rader DJ, Tall AR. Ai D, et al. Among authors: conlon dm. J Clin Invest. 2012 May;122(5):1677-87. doi: 10.1172/JCI61248. Epub 2012 Apr 2. J Clin Invest. 2012. PMID: 22466652 Free PMC article.

2

The conversion of apoB100 low density lipoprotein/high density lipoprotein particles to apoB100 very low density lipoproteins in response to oleic acid occurs in the endoplasmic reticulum and not in the Golgi in McA RH7777 cells.

Yamaguchi J, Gamble MV, Conlon D, Liang JS, Ginsberg HN. Yamaguchi J, et al. J Biol Chem. 2003 Oct 24;278(43):42643-51. doi: 10.1074/jbc.M306920200. Epub 2003 Aug 12. J Biol Chem. 2003. PMID: 12917397 Free article.

3

Translocation efficiency of apolipoprotein B is determined by the presence of beta-sheet domains, not pause transfer sequences.

Yamaguchi J, Conlon DM, Liang JJ, Fisher EA, Ginsberg HN. Yamaguchi J, et al. Among authors: conlon dm. J Biol Chem. 2006 Sep 15;281(37):27063-71. doi: 10.1074/jbc.M606809200. Epub 2006 Jul 19. J Biol Chem. 2006. PMID: 16854991 Free article.

4

Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis.

Zhang YL, Hernandez-Ono A, Siri P, Weisberg S, Conlon D, Graham MJ, Crooke RM, Huang LS, Ginsberg HN. Zhang YL, et al. J Biol Chem. 2006 Dec 8;281(49):37603-15. doi: 10.1074/jbc.M604709200. Epub 2006 Sep 12. J Biol Chem. 2006. PMID: 16971390 Free article.

5

Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy.

Caviglia JM, Gayet C, Ota T, Hernandez-Ono A, Conlon DM, Jiang H, Fisher EA, Ginsberg HN. Caviglia JM, et al. Among authors: conlon dm. J Lipid Res. 2011 Sep;52(9):1636-51. doi: 10.1194/jlr.M016931. Epub 2011 Jun 30. J Lipid Res. 2011. PMID: 21719579 Free PMC article.

6

Autophagy and cardiometabolic risk factors.

Juárez-Rojas JG, Reyes-Soffer G, Conlon D, Ginsberg HN. Juárez-Rojas JG, et al. Rev Endocr Metab Disord. 2014 Dec;15(4):307-15. doi: 10.1007/s11154-014-9295-7. Rev Endocr Metab Disord. 2014. PMID: 25246308 Free PMC article. Review.

7

Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis.

Conlon DM, Thomas T, Fedotova T, Hernandez-Ono A, Di Paolo G, Chan RB, Ruggles K, Gibeley S, Liu J, Ginsberg HN. Conlon DM, et al. J Clin Invest. 2016 Oct 3;126(10):3852-3867. doi: 10.1172/JCI86028. Epub 2016 Sep 6. J Clin Invest. 2016. PMID: 27599291 Free PMC article.

8

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.

Liu Y, Conlon DM, Bi X, Slovik KJ, Shi J, Edelstein HI, Millar JS, Javaheri A, Cuchel M, Pashos EE, Iqbal J, Hussain MM, Hegele RA, Yang W, Duncan SA, Rader DJ, Morrisey EE. Liu Y, et al. Among authors: conlon dm. Cell Rep. 2017 May 16;19(7):1456-1466. doi: 10.1016/j.celrep.2017.04.064. Cell Rep. 2017. PMID: 28514664 Free PMC article.

9

Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism.

Abbey D, Conlon D, Rainville C, Elwyn S, Quiroz-Figueroa K, Billheimer J, Schultz DC, Hand NJ, Cherry S, Rader DJ. Abbey D, et al. Clin Transl Sci. 2021 Jul;14(4):1369-1379. doi: 10.1111/cts.12988. Epub 2021 Jun 22. Clin Transl Sci. 2021. PMID: 34156146 Free PMC article.

10

TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes.

Quiroz-Figueroa K, Vitali C, Conlon DM, Millar JS, Tobias JW, Bauer RC, Hand NJ, Rader DJ. Quiroz-Figueroa K, et al. Among authors: conlon dm. J Clin Invest. 2021 Nov 15;131(22):e146775. doi: 10.1172/JCI146775. J Clin Invest. 2021. PMID: 34779419 Free PMC article.

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