Desai A - Search Results

1

The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry.

Huang B, Kukowska-Latallo JF, Tang S, Zong H, Johnson KB, Desai A, Gordon CL, Leroueil PR, Baker JR Jr. Huang B, et al. Among authors: desai a. Bioorg Med Chem Lett. 2012 May 1;22(9):3152-6. doi: 10.1016/j.bmcl.2012.03.052. Epub 2012 Mar 21. Bioorg Med Chem Lett. 2012. PMID: 22480432 Free PMC article.

2

RGD dendron bodies; synthetic avidity agents with defined and potentially interchangeable effector sites that can substitute for antibodies.

McNerny DQ, Kukowska-Latallo JF, Mullen DG, Wallace JM, Desai AM, Shukla R, Huang B, Banaszak Holl MM, Baker JR Jr. McNerny DQ, et al. Bioconjug Chem. 2009 Oct 21;20(10):1853-9. doi: 10.1021/bc900217h. Bioconjug Chem. 2009. PMID: 20711425 Free PMC article.

3

Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent.

Zhang Y, Thomas TP, Lee KH, Li M, Zong H, Desai AM, Kotlyar A, Huang B, Holl MM, Baker JR Jr. Zhang Y, et al. Among authors: desai am. Bioorg Med Chem. 2011 Apr 15;19(8):2557-64. doi: 10.1016/j.bmc.2011.03.019. Epub 2011 Mar 12. Bioorg Med Chem. 2011. PMID: 21459000 Free PMC article.

4

Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio.

Zong H, Thomas TP, Lee KH, Desai AM, Li MH, Kotlyar A, Zhang Y, Leroueil PR, Gam JJ, Banaszak Holl MM, Baker JR Jr. Zong H, et al. Among authors: desai am. Biomacromolecules. 2012 Apr 9;13(4):982-91. doi: 10.1021/bm201639c. Epub 2012 Mar 30. Biomacromolecules. 2012. PMID: 22360561

5

Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.

Thomas TP, Huang B, Choi SK, Silpe JE, Kotlyar A, Desai AM, Zong H, Gam J, Joice M, Baker JR Jr. Thomas TP, et al. Among authors: desai am. Mol Pharm. 2012 Sep 4;9(9):2669-2676. doi: 10.1021/mp3002232. Epub 2012 Aug 7. Mol Pharm. 2012. PMID: 22827500 Free PMC article.

6

Design considerations for PAMAM dendrimer therapeutics.

Goonewardena SN, Kratz JD, Zong H, Desai AM, Tang S, Emery S, Baker JR Jr, Huang B. Goonewardena SN, et al. Bioorg Med Chem Lett. 2013 May 15;23(10):2872-5. doi: 10.1016/j.bmcl.2013.03.088. Epub 2013 Apr 1. Bioorg Med Chem Lett. 2013. PMID: 23583511

7

Human plasma-mediated hypoxic activation of indolequinone-based naloxone pro-drugs.

Huang B, Tang S, Desai A, Cheng XM, Kotlyar A, Van Der Spek A, Thomas TP, Baker JR Jr. Huang B, et al. Among authors: desai a. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5016-20. doi: 10.1016/j.bmcl.2009.07.061. Epub 2009 Jul 12. Bioorg Med Chem Lett. 2009. PMID: 19632838

8

Targeted dendrimeric anticancer prodrug: a methotrexate-folic acid-poly(amidoamine) conjugate and a novel, rapid, "one pot" synthetic approach.

Zhang Y, Thomas TP, Desai A, Zong H, Leroueil PR, Majoros IJ, Baker JR Jr. Zhang Y, et al. Among authors: desai a. Bioconjug Chem. 2010 Mar 17;21(3):489-95. doi: 10.1021/bc9003958. Epub 2010 Feb 3. Bioconjug Chem. 2010. PMID: 20128612 Free PMC article.

9

The synthesis of a c(RGDyK) targeted SN38 prodrug with an indolequinone structure for bioreductive drug release.

Huang B, Desai A, Tang S, Thomas TP, Baker JR Jr. Huang B, et al. Among authors: desai a. Org Lett. 2010 Apr 2;12(7):1384-7. doi: 10.1021/ol1002626. Org Lett. 2010. PMID: 20192275 Free PMC article.

10

Plasma-mediated release of morphine from synthesized prodrugs.

Thomas TP, Huang B, Desai A, Zong H, Cheng XM, Kotlyar A, Leroueil PR, Dunham T, van der Spek A, Ward BB, Baker JR Jr. Thomas TP, et al. Among authors: desai a. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6250-3. doi: 10.1016/j.bmcl.2010.08.098. Epub 2010 Aug 24. Bioorg Med Chem Lett. 2010. PMID: 20833544

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