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The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.
Robert G, Gastaldi C, Puissant A, Hamouda A, Jacquel A, Dufies M, Belhacene N, Colosetti P, Reed JC, Auberger P, Luciano F. Robert G, et al. Among authors: colosetti p. Autophagy. 2012 Apr;8(4):637-49. doi: 10.4161/auto.19084. Epub 2012 Apr 1. Autophagy. 2012. PMID: 22498477 Free PMC article.
BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice.
Hamouda MA, Jacquel A, Robert G, Puissant A, Richez V, Cassel R, Fenouille N, Roulland S, Gilleron J, Griessinger E, Dubois A, Bailly-Maitre B, Goncalves D, Mallavialle A, Colosetti P, Marchetti S, Amiot M, Gomez-Bougie P, Rochet N, Deckert M, Avet-Loiseau H, Hofman P, Karsenti JM, Jeandel PY, Blin-Wakkach C, Nadel B, Cluzeau T, Anderson KC, Fuzibet JG, Auberger P, Luciano F. Hamouda MA, et al. Among authors: colosetti p. J Exp Med. 2016 Aug 22;213(9):1705-22. doi: 10.1084/jem.20150983. Epub 2016 Jul 25. J Exp Med. 2016. PMID: 27455953 Free PMC article.
Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux.
Giuliano S, Cormerais Y, Dufies M, Grépin R, Colosetti P, Belaid A, Parola J, Martin A, Lacas-Gervais S, Mazure NM, Benhida R, Auberger P, Mograbi B, Pagès G. Giuliano S, et al. Among authors: colosetti p. Autophagy. 2015;11(10):1891-904. doi: 10.1080/15548627.2015.1085742. Autophagy. 2015. PMID: 26312386 Free PMC article.
The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.
Aira LE, Villa E, Colosetti P, Gamas P, Signetti L, Obba S, Proics E, Gautier F, Bailly-Maitre B, Jacquel A, Robert G, Luciano F, Juin PP, Ricci JE, Auberger P, Marchetti S. Aira LE, et al. Among authors: colosetti p. Oncogene. 2018 Apr;37(16):2122-2136. doi: 10.1038/s41388-017-0112-0. Epub 2018 Feb 2. Oncogene. 2018. PMID: 29391601
55 results