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Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion.
Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. Gorboulev V, et al. Among authors: koepsell h. Diabetes. 2012 Jan;61(1):187-96. doi: 10.2337/db11-1029. Epub 2011 Nov 28. Diabetes. 2012. PMID: 22124465 Free PMC article.
Antidiabetic Effects of a Tripeptide That Decreases Abundance of Na+-d-glucose Cotransporter SGLT1 in the Brush-Border Membrane of the Small Intestine.
Otto C, Friedrich A, Vrhovac Madunić I, Baumeier C, Schwenk RW, Karaica D, Germer CT, Schürmann A, Sabolić I, Koepsell H. Otto C, et al. Among authors: koepsell h. ACS Omega. 2020 Nov 4;5(45):29127-29139. doi: 10.1021/acsomega.0c03844. eCollection 2020 Nov 17. ACS Omega. 2020. PMID: 33225144 Free PMC article.
Phosphorylation of RS1 (RSC1A1) Steers Inhibition of Different Exocytotic Pathways for Glucose Transporter SGLT1 and Nucleoside Transporter CNT1, and an RS1-Derived Peptide Inhibits Glucose Absorption.
Veyhl-Wichmann M, Friedrich A, Vernaleken A, Singh S, Kipp H, Gorboulev V, Keller T, Chintalapati C, Pipkorn R, Pastor-Anglada M, Groll J, Koepsell H. Veyhl-Wichmann M, et al. Among authors: koepsell h. Mol Pharmacol. 2016 Jan;89(1):118-32. doi: 10.1124/mol.115.101162. Epub 2015 Oct 13. Mol Pharmacol. 2016. PMID: 26464324
246 results