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Hepatic lipid droplet-associated proteome changes distinguish dietary-induced fatty liver from glucose tolerance in male mice.
Van Woerkom A, Harney DJ, Nagarajan SR, Hakeem-Sanni MF, Lin J, Hooke M, Pulpitel T, Cooney GJ, Larance M, Saunders DN, Brandon AE, Hoy AJ. Van Woerkom A, et al. Among authors: saunders dn. Am J Physiol Endocrinol Metab. 2024 Jun 1;326(6):E842-E855. doi: 10.1152/ajpendo.00013.2024. Epub 2024 Apr 24. Am J Physiol Endocrinol Metab. 2024. PMID: 38656127 Free PMC article.
ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis.
Farrawell NE, Bax M, McAlary L, McKenna J, Maksour S, Do-Ha D, Rayner SL, Blair IP, Chung RS, Yerbury JJ, Ooi L, Saunders DN. Farrawell NE, et al. Among authors: saunders dn. Hum Mol Genet. 2023 Jul 4;32(14):2386-2398. doi: 10.1093/hmg/ddad063. Hum Mol Genet. 2023. PMID: 37220877 Free PMC article.
Proteostasis impairment and ALS.
Lambert-Smith IA, Saunders DN, Yerbury JJ. Lambert-Smith IA, et al. Among authors: saunders dn. Prog Biophys Mol Biol. 2022 Oct;174:3-27. doi: 10.1016/j.pbiomolbio.2022.06.001. Epub 2022 Jun 15. Prog Biophys Mol Biol. 2022. PMID: 35716729 Review.
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS.
Farrawell NE, McAlary L, Lum JS, Chisholm CG, Warraich ST, Blair IP, Vine KL, Saunders DN, Yerbury JJ. Farrawell NE, et al. Among authors: saunders dn. iScience. 2020 Oct 20;23(11):101700. doi: 10.1016/j.isci.2020.101700. eCollection 2020 Nov 20. iScience. 2020. PMID: 33196025 Free PMC article.
MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer.
Cipponi A, Goode DL, Bedo J, McCabe MJ, Pajic M, Croucher DR, Rajal AG, Junankar SR, Saunders DN, Lobachevsky P, Papenfuss AT, Nessem D, Nobis M, Warren SC, Timpson P, Cowley M, Vargas AC, Qiu MR, Generali DG, Keerthikumar S, Nguyen U, Corcoran NM, Long GV, Blay JY, Thomas DM. Cipponi A, et al. Among authors: saunders dn. Science. 2020 Jun 5;368(6495):1127-1131. doi: 10.1126/science.aau8768. Science. 2020. PMID: 32499442
67 results