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Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis.
De Semir D, Nosrati M, Bezrookove V, Dar AA, Federman S, Bienvenu G, Venna S, Rangel J, Climent J, Meyer Tamgüney TM, Thummala S, Tong S, Leong SP, Haqq C, Billings P, Miller JR 3rd, Sagebiel RW, Debs R, Kashani-Sabet M. De Semir D, et al. Among authors: debs r. Proc Natl Acad Sci U S A. 2012 May 1;109(18):7067-72. doi: 10.1073/pnas.1119949109. Epub 2012 Apr 17. Proc Natl Acad Sci U S A. 2012. PMID: 22511720 Free PMC article.
Antitumor activity of miR-1280 in melanoma by regulation of Src.
Sun V, Zhou WB, Nosrati M, Majid S, Thummala S, de Semir D, Bezrookove V, de Feraudy S, Chun L, Schadendorf D, Debs R, Kashani-Sabet M, Dar AA. Sun V, et al. Among authors: debs r. Mol Ther. 2015 Jan;23(1):71-8. doi: 10.1038/mt.2014.176. Epub 2014 Sep 8. Mol Ther. 2015. PMID: 25195599 Free PMC article.
The role of BPTF in melanoma progression and in response to BRAF-targeted therapy.
Dar AA, Nosrati M, Bezrookove V, de Semir D, Majid S, Thummala S, Sun V, Tong S, Leong SP, Minor D, Billings PR, Soroceanu L, Debs R, Miller JR 3rd, Sagebiel RW, Kashani-Sabet M. Dar AA, et al. Among authors: debs r. J Natl Cancer Inst. 2015 Feb 23;107(5):djv034. doi: 10.1093/jnci/djv034. J Natl Cancer Inst. 2015. PMID: 25713167 Free PMC article.
BPTF transduces MITF-driven prosurvival signals in melanoma cells.
Dar AA, Majid S, Bezrookove V, Phan B, Ursu S, Nosrati M, De Semir D, Sagebiel RW, Miller JR 3rd, Debs R, Cleaver JE, Kashani-Sabet M. Dar AA, et al. Among authors: debs r. Proc Natl Acad Sci U S A. 2016 May 31;113(22):6254-8. doi: 10.1073/pnas.1606027113. Epub 2016 May 16. Proc Natl Acad Sci U S A. 2016. PMID: 27185926 Free PMC article.
Genes and pathways downstream of telomerase in melanoma metastasis.
Bagheri S, Nosrati M, Li S, Fong S, Torabian S, Rangel J, Moore DH, Federman S, Laposa RR, Baehner FL, Sagebiel RW, Cleaver JE, Haqq C, Debs RJ, Blackburn EH, Kashani-Sabet M. Bagheri S, et al. Among authors: debs rj. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11306-11. doi: 10.1073/pnas.0510085103. Epub 2006 Jul 17. Proc Natl Acad Sci U S A. 2006. PMID: 16847266 Free PMC article.
PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
de Semir D, Bezrookove V, Nosrati M, Dar AA, Wu C, Shen J, Rieken C, Venkatasubramanian M, Miller JR 3rd, Desprez PY, McAllister S, Soroceanu L, Debs RJ, Salomonis N, Schadendorf D, Cleaver JE, Kashani-Sabet M. de Semir D, et al. Among authors: debs rj. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5766-E5775. doi: 10.1073/pnas.1804779115. Epub 2018 Jun 4. Proc Natl Acad Sci U S A. 2018. PMID: 29866840 Free PMC article.
PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex.
de Semir D, Bezrookove V, Nosrati M, Scanlon KR, Singer E, Judkins J, Rieken C, Wu C, Shen J, Schmudermayer C, Dar AA, Miller JR 3rd, Cobbs C, Yount G, Desprez PY, Debs RJ, Salomonis N, McAllister S, Cleaver JE, Soroceanu L, Kashani-Sabet M. de Semir D, et al. Among authors: debs rj. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):9064-9073. doi: 10.1073/pnas.1914505117. Epub 2020 Apr 9. Proc Natl Acad Sci U S A. 2020. PMID: 32273388 Free PMC article.
Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Dar AA, Bezrookove V, Nosrati M, Ice R, Patino JM, Vaquero EM, Parrett B, Leong SP, Kim KB, Debs RJ, Soroceanu L, Miller JR 3rd, Desprez PY, Cleaver JE, Salomonis N, McAllister S, Kashani-Sabet M. Dar AA, et al. Among authors: debs rj. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206824119. doi: 10.1073/pnas.2206824119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969744 Free PMC article.
148 results