Nishioka K - Search Results

1

Discovery of potent and orally bioavailable 17β-hydroxysteroid dehydrogenase type 3 inhibitors.

Harada K, Kubo H, Abe J, Haneta M, Conception A, Inoue S, Okada S, Nishioka K. Harada K, et al. Among authors: nishioka k. Bioorg Med Chem. 2012 May 15;20(10):3242-54. doi: 10.1016/j.bmc.2012.03.052. Epub 2012 Apr 1. Bioorg Med Chem. 2012. PMID: 22512907

2

Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer.

Harada K, Kubo H, Tomigahara Y, Nishioka K, Takahashi J, Momose M, Inoue S, Kojima A. Harada K, et al. Among authors: nishioka k. Bioorg Med Chem Lett. 2010 Jan 1;20(1):272-5. doi: 10.1016/j.bmcl.2009.10.111. Epub 2009 Nov 10. Bioorg Med Chem Lett. 2010. PMID: 19954971

3

Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors.

Harada K, Kubo H, Tanaka A, Nishioka K. Harada K, et al. Among authors: nishioka k. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7. doi: 10.1016/j.bmcl.2011.10.095. Epub 2011 Nov 12. Bioorg Med Chem Lett. 2012. PMID: 22137341

4

Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19.

Shirotani N, Togawa M, Ikushiro S, Sakaki T, Harada T, Miyagawa H, Matsui M, Nagahori H, Mikata K, Nishioka K, Hirai N, Akamatsu M. Shirotani N, et al. Among authors: nishioka k. Bioorg Med Chem. 2015 Oct 15;23(20):6594-601. doi: 10.1016/j.bmc.2015.09.019. Epub 2015 Sep 11. Bioorg Med Chem. 2015. PMID: 26404412 Free article.

5

Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes.

Hirose Y, Nagahori H, Yamada T, Deguchi Y, Tomigahara Y, Nishioka K, Uwagawa S, Kawamura S, Isobe N, Lake BG, Okuno Y. Hirose Y, et al. Among authors: nishioka k. Toxicology. 2009 Apr 5;258(1):64-9. doi: 10.1016/j.tox.2009.01.007. Toxicology. 2009. PMID: 19378387

6

In vitro metabolism of trans-permethrin and its major metabolites, PBalc and PBacid, in humans.

Takaku T, Mikata K, Matsui M, Nishioka K, Isobe N, Kaneko H. Takaku T, et al. Among authors: nishioka k. J Agric Food Chem. 2011 May 11;59(9):5001-5. doi: 10.1021/jf200032q. Epub 2011 Apr 8. J Agric Food Chem. 2011. PMID: 21456540

7

Mode of action analysis for the synthetic pyrethroid metofluthrin-induced rat liver tumors: evidence for hepatic CYP2B induction and hepatocyte proliferation.

Deguchi Y, Yamada T, Hirose Y, Nagahori H, Kushida M, Sumida K, Sukata T, Tomigahara Y, Nishioka K, Uwagawa S, Kawamura S, Okuno Y. Deguchi Y, et al. Among authors: nishioka k. Toxicol Sci. 2009 Mar;108(1):69-80. doi: 10.1093/toxsci/kfp006. Epub 2009 Jan 27. Toxicol Sci. 2009. PMID: 19176366

8

Metabolomic and transcriptomic profiling of human K-ras oncogene transgenic rats with pancreatic ductal adenocarcinomas.

Yabushita S, Fukamachi K, Tanaka H, Fukuda T, Sumida K, Deguchi Y, Mikata K, Nishioka K, Kawamura S, Uwagawa S, Suzui M, Alexander DB, Tsuda H. Yabushita S, et al. Among authors: nishioka k. Carcinogenesis. 2013 Jun;34(6):1251-9. doi: 10.1093/carcin/bgt053. Epub 2013 Feb 7. Carcinogenesis. 2013. PMID: 23393225

9

14C-labeling of bromobutide, 2-bromo-3,3-dimethyl-N-(alpha, alpha-dimethylbenzyl)butyramide.

Kanamaru H, Nishioka K, Komori H, Kawahara K. Kanamaru H, et al. Among authors: nishioka k. Radioisotopes. 1988 Jan;37(1):1-6. doi: 10.3769/radioisotopes.37.1. Radioisotopes. 1988. PMID: 3375464

10

An improved method for 14C-labelling of farnesylacetic acid and its geranyl ester.

Nishioka K, Nakatsuka I, Kanamaru H. Nishioka K, et al. Radioisotopes. 1988 Mar;37(3):133-9. doi: 10.3769/radioisotopes.37.3_133. Radioisotopes. 1988. PMID: 3387600

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