Khan M - Search Results

1

Role of misfolded N-CoR mediated transcriptional deregulation of Flt3 in acute monocytic leukemia (AML)-M5 subtype.

Nin DS, Kok WK, Li F, Takahashi S, Chng WJ, Khan M. Nin DS, et al. Among authors: khan m. PLoS One. 2012;7(4):e34501. doi: 10.1371/journal.pone.0034501. Epub 2012 Apr 13. PLoS One. 2012. PMID: 22514634 Free PMC article.

2

Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.

Ng AP, Nin DS, Fong JH, Venkataraman D, Chen CS, Khan M. Ng AP, et al. Among authors: khan m. Mol Cancer Ther. 2007 Aug;6(8):2240-8. doi: 10.1158/1535-7163.MCT-06-0705. Mol Cancer Ther. 2007. PMID: 17699721 Free article.

3

Curcumin sensitizes acute promyelocytic leukemia cells to unfolded protein response-induced apoptosis by blocking the loss of misfolded N-CoR protein.

Ng AP, Chng WJ, Khan M. Ng AP, et al. Among authors: khan m. Mol Cancer Res. 2011 Jul;9(7):878-88. doi: 10.1158/1541-7786.MCR-10-0545. Epub 2011 May 20. Mol Cancer Res. 2011. PMID: 21602299 Free article.

4

Role of chaperone mediated autophagy (CMA) in the degradation of misfolded N-CoR protein in non-small cell lung cancer (NSCLC) cells.

Ali AB, Nin DS, Tam J, Khan M. Ali AB, et al. Among authors: khan m. PLoS One. 2011;6(9):e25268. doi: 10.1371/journal.pone.0025268. Epub 2011 Sep 23. PLoS One. 2011. PMID: 21966475 Free PMC article.

5

Akt-induced phosphorylation of N-CoR at serine 1450 contributes to its misfolded conformational dependent loss (MCDL) in acute myeloid leukemia of the M5 subtype.

Nin DS, Ali AB, Okumura K, Asou N, Chen CS, Chng WJ, Khan M. Nin DS, et al. Among authors: khan m. PLoS One. 2013 Aug 5;8(8):e70891. doi: 10.1371/journal.pone.0070891. Print 2013. PLoS One. 2013. PMID: 23940660 Free PMC article.

6

Misfolded N-CoR is Linked to the Ectopic Reactivation of CD34/Flt3-Based Stem-Cell Phenotype in Promyelocytic and Monocytic Acute Myeloid Leukemia.

Nin DS, Li F, Visvanathan S, Khan M. Nin DS, et al. Among authors: khan m. Front Oncol. 2015 Oct 7;5:210. doi: 10.3389/fonc.2015.00210. eCollection 2015. Front Oncol. 2015. PMID: 26500885 Free PMC article.

7

Interplay of protein misfolding pathway and unfolded-protein response in acute promyelocytic leukemia.

Khan M. Khan M. Expert Rev Proteomics. 2010 Aug;7(4):591-600. doi: 10.1586/epr.10.38. Expert Rev Proteomics. 2010. PMID: 20653512 Review.

8

Curcumin analogues with potent and selective anti-proliferative activity on acute promyelocytic leukemia: involvement of accumulated misfolded nuclear receptor co-repressor (N-CoR) protein as a basis for selective activity.

Tan KL, Koh SB, Ee RP, Khan M, Go ML. Tan KL, et al. Among authors: khan m. ChemMedChem. 2012 Sep;7(9):1567-79. doi: 10.1002/cmdc.201200293. Epub 2012 Aug 6. ChemMedChem. 2012. PMID: 22887959

9

Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosis.

Ng AP, Howe Fong J, Sijin Nin D, Hirpara JL, Asou N, Chen CS, Pervaiz S, Khan M. Ng AP, et al. Among authors: khan m. Cancer Res. 2006 Oct 15;66(20):9903-12. doi: 10.1158/0008-5472.CAN-06-0002. Cancer Res. 2006. PMID: 17047052

10

Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling.

Shen J, Tai YC, Zhou J, Stephen Wong CH, Cheang PT, Fred Wong WS, Xie Z, Khan M, Han JH, Chen CS. Shen J, et al. Among authors: khan m. Exp Hematol. 2007 Jan;35(1):75-83. doi: 10.1016/j.exphem.2006.09.007. Exp Hematol. 2007. PMID: 17198876 Free article.

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