Hu Z - Search Results

1

Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model.

Hu Z, Gupta J, Zhang Z, Gerseny H, Berg A, Chen YJ, Zhang Z, Du H, Brendler CB, Xiao X, Pienta KJ, Guise T, Lee C, Stern PH, Stock S, Seth P. Hu Z, et al. Hum Gene Ther. 2012 Aug;23(8):871-82. doi: 10.1089/hum.2012.040. Epub 2012 Jun 25. Hum Gene Ther. 2012. PMID: 22551458 Free PMC article.

2

A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGFbeta signaling for breast cancer therapy.

Hu Z, Robbins JS, Pister A, Zafar MB, Zhang ZW, Gupta J, Lee KJ, Newman K, Yun CO, Guise T, Seth P. Hu Z, et al. Cancer Gene Ther. 2010 Apr;17(4):235-43. doi: 10.1038/cgt.2009.72. Epub 2009 Oct 2. Cancer Gene Ther. 2010. PMID: 19798122 Free PMC article.

3

Systemic delivery of an oncolytic adenovirus expressing soluble transforming growth factor-β receptor II-Fc fusion protein can inhibit breast cancer bone metastasis in a mouse model.

Hu Z, Zhang Z, Guise T, Seth P. Hu Z, et al. Hum Gene Ther. 2010 Nov;21(11):1623-9. doi: 10.1089/hum.2010.018. Epub 2010 Sep 9. Hum Gene Ther. 2010. PMID: 20712434 Free PMC article.

4

Systemic delivery of a novel liver-detargeted oncolytic adenovirus causes reduced liver toxicity but maintains the antitumor response in a breast cancer bone metastasis model.

Zhang Z, Krimmel J, Zhang Z, Hu Z, Seth P. Zhang Z, et al. Among authors: hu z. Hum Gene Ther. 2011 Sep;22(9):1137-42. doi: 10.1089/hum.2011.003. Epub 2011 Jun 8. Hum Gene Ther. 2011. PMID: 21480822 Free PMC article.

5

Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer.

Hu Z, Gerseny H, Zhang Z, Chen YJ, Berg A, Zhang Z, Stock S, Seth P. Hu Z, et al. Mol Ther. 2011 Sep;19(9):1609-18. doi: 10.1038/mt.2011.114. Epub 2011 Jun 28. Mol Ther. 2011. PMID: 21712815 Free PMC article.

6

Intravenous administration of adenoviruses targeting transforming growth factor beta signaling inhibits established bone metastases in 4T1 mouse mammary tumor model in an immunocompetent syngeneic host.

Zhang Z, Hu Z, Gupta J, Krimmel JD, Gerseny HM, Berg AF, Robbins JS, Du H, Prabhakar B, Seth P. Zhang Z, et al. Among authors: hu z. Cancer Gene Ther. 2012 Sep;19(9):630-6. doi: 10.1038/cgt.2012.41. Epub 2012 Jun 29. Cancer Gene Ther. 2012. PMID: 22744210 Free PMC article.

7

Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases.

Xu W, Zhang Z, Yang Y, Hu Z, Wang CH, Morgan M, Wu Y, Hutten R, Xiao X, Stock S, Guise T, Prabhakar BS, Brendler C, Seth P. Xu W, et al. Among authors: hu z. Mol Ther. 2014 Aug;22(8):1504-1517. doi: 10.1038/mt.2014.80. Epub 2014 May 5. Mol Ther. 2014. PMID: 24791939 Free PMC article.

8

The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer.

Xu W, Neill T, Yang Y, Hu Z, Cleveland E, Wu Y, Hutten R, Xiao X, Stock SR, Shevrin D, Kaul K, Brendler C, Iozzo RV, Seth P. Xu W, et al. Among authors: hu z. Gene Ther. 2015 Mar;22(3):247-56. doi: 10.1038/gt.2014.110. Epub 2014 Dec 11. Gene Ther. 2015. PMID: 25503693 Free PMC article.

9

Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases.

Yang Y, Xu W, Neill T, Hu Z, Wang CH, Xiao X, Stock SR, Guise T, Yun CO, Brendler CB, Iozzo RV, Seth P. Yang Y, et al. Among authors: hu z. Hum Gene Ther. 2015 Dec;26(12):813-25. doi: 10.1089/hum.2015.098. Epub 2015 Nov 10. Hum Gene Ther. 2015. PMID: 26467629 Free PMC article.

10

LyP-1-Modified Oncolytic Adenoviruses Targeting Transforming Growth Factor β Inhibit Tumor Growth and Metastases and Augment Immune Checkpoint Inhibitor Therapy in Breast Cancer Mouse Models.

Xu W, Yang Y, Hu Z, Head M, Mangold KA, Sullivan M, Wang E, Saha P, Gulukota K, Helseth DL, Guise T, Prabhkar BS, Kaul K, Schreiber H, Seth P. Xu W, et al. Among authors: hu z. Hum Gene Ther. 2020 Aug;31(15-16):863-880. doi: 10.1089/hum.2020.078. Epub 2020 Jun 12. Hum Gene Ther. 2020. PMID: 32394753 Free PMC article.

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