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Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.
Castaño Betancourt MC, Cailotto F, Kerkhof HJ, Cornelis FM, Doherty SA, Hart DJ, Hofman A, Luyten FP, Maciewicz RA, Mangino M, Metrustry S, Muir K, Peters MJ, Rivadeneira F, Wheeler M, Zhang W, Arden N, Spector TD, Uitterlinden AG, Doherty M, Lories RJ, Valdes AM, van Meurs JB. Castaño Betancourt MC, et al. Among authors: muir k. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8218-23. doi: 10.1073/pnas.1119899109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566624 Free PMC article.
The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance.
Valdes AM, Evangelou E, Kerkhof HJ, Tamm A, Doherty SA, Kisand K, Tamm A, Kerna I, Uitterlinden A, Hofman A, Rivadeneira F, Cooper C, Dennison EM, Zhang W, Muir KR, Ioannidis JP, Wheeler M, Maciewicz RA, van Meurs JB, Arden NK, Spector TD, Doherty M. Valdes AM, et al. Among authors: muir kr. Ann Rheum Dis. 2011 May;70(5):873-5. doi: 10.1136/ard.2010.134155. Epub 2010 Sep 24. Ann Rheum Dis. 2011. PMID: 20870806 Free PMC article. No abstract available.
Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.
Valdes AM, Arden NK, Vaughn FL, Doherty SA, Leaverton PE, Zhang W, Muir KR, Rampersaud E, Dennison EM, Edwards MH, Jameson KA, Javaid MK, Spector TD, Cooper C, Maciewicz RA, Doherty M. Valdes AM, et al. Among authors: muir kr. Arthritis Care Res (Hoboken). 2011 Mar;63(3):440-4. doi: 10.1002/acr.20375. Epub 2010 Oct 28. Arthritis Care Res (Hoboken). 2011. PMID: 21031562 Free article.
Nottingham knee osteoarthritis risk prediction models.
Zhang W, McWilliams DF, Ingham SL, Doherty SA, Muthuri S, Muir KR, Doherty M. Zhang W, et al. Ann Rheum Dis. 2011 Sep;70(9):1599-604. doi: 10.1136/ard.2011.149807. Epub 2011 May 25. Ann Rheum Dis. 2011. PMID: 21613308
The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis.
Valdes AM, De Wilde G, Doherty SA, Lories RJ, Vaughn FL, Laslett LL, Maciewicz RA, Soni A, Hart DJ, Zhang W, Muir KR, Dennison EM, Wheeler M, Leaverton P, Cooper C, Spector TD, Cicuttini FM, Chapman V, Jones G, Arden NK, Doherty M. Valdes AM, et al. Among authors: muir kr. Ann Rheum Dis. 2011 Sep;70(9):1556-61. doi: 10.1136/ard.2010.148122. Epub 2011 May 25. Ann Rheum Dis. 2011. PMID: 21616913 Free PMC article.
1,161 results