Rooney C - Search Results

1

Structure-activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: part 2.

Delouvrié B, Al-Kadhimi K, Arnould JC, Barry ST, Cross DA, Didelot M, Gavine PR, Germain H, Harris CS, Hughes AM, Jude DA, Kendrew J, Lambert-van der Brempt C, Lohmann JJ, Ménard M, Mortlock AA, Pass M, Rooney C, Vautier M, Vincent JL, Warin N. Delouvrié B, et al. Among authors: rooney c. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4117-21. doi: 10.1016/j.bmcl.2012.04.061. Epub 2012 Apr 21. Bioorg Med Chem Lett. 2012. PMID: 22572578

2

Structure-activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: part 1.

Delouvrié B, Al-Kadhimi K, Arnould JC, Barry ST, Cross DA, Didelot M, Gavine PR, Germain H, Harris CS, Hughes AM, Jude DA, Kendrew J, Lambert-van der Brempt C, Lohmann JJ, Ménard M, Mortlock AA, Pass M, Rooney C, Vautier M, Vincent JL, Warin N. Delouvrié B, et al. Among authors: rooney c. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4111-6. doi: 10.1016/j.bmcl.2012.04.063. Epub 2012 Apr 21. Bioorg Med Chem Lett. 2012. PMID: 22575869

3

AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family.

Gavine PR, Mooney L, Kilgour E, Thomas AP, Al-Kadhimi K, Beck S, Rooney C, Coleman T, Baker D, Mellor MJ, Brooks AN, Klinowska T. Gavine PR, et al. Among authors: rooney c. Cancer Res. 2012 Apr 15;72(8):2045-56. doi: 10.1158/0008-5472.CAN-11-3034. Epub 2012 Feb 27. Cancer Res. 2012. PMID: 22369928

4

E-Cadherin and EpCAM expression by NSCLC tumour cells associate with normal fibroblast activation through a pathway initiated by integrin αvβ6 and maintained through TGFβ signalling.

Eberlein C, Rooney C, Ross SJ, Farren M, Weir HM, Barry ST. Eberlein C, et al. Among authors: rooney c. Oncogene. 2015 Feb 5;34(6):704-16. doi: 10.1038/onc.2013.600. Epub 2014 Feb 3. Oncogene. 2015. PMID: 24488011

5

A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo.

Eberlein C, Kendrew J, McDaid K, Alfred A, Kang JS, Jacobs VN, Ross SJ, Rooney C, Smith NR, Rinkenberger J, Cao A, Churchman A, Marshall JF, Weir HM, Bedian V, Blakey DC, Foltz IN, Barry ST. Eberlein C, et al. Among authors: rooney c. Oncogene. 2013 Sep 12;32(37):4406-16. doi: 10.1038/onc.2012.460. Epub 2012 Oct 29. Oncogene. 2013. PMID: 23108397

6

Characterization of FGFR1 Locus in sqNSCLC Reveals a Broad and Heterogeneous Amplicon.

Rooney C, Geh C, Williams V, Heuckmann JM, Menon R, Schneider P, Al-Kadhimi K, Dymond M, Smith NR, Baker D, French T, Smith PD, Harrington EA, Barrett JC, Kilgour E. Rooney C, et al. PLoS One. 2016 Feb 23;11(2):e0149628. doi: 10.1371/journal.pone.0149628. eCollection 2016. PLoS One. 2016. PMID: 26905262 Free PMC article.

7

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogues of 3-aminopyridin-2(1H)-one.

Saari WS, Wai JS, Fisher TE, Thomas CM, Hoffman JM, Rooney CS, Smith AM, Jones JH, Bamberger DL, Goldman ME, et al. Saari WS, et al. Among authors: rooney cs. J Med Chem. 1992 Oct 16;35(21):3792-802. doi: 10.1021/jm00099a007. J Med Chem. 1992. PMID: 1279173

8

Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one.

Wai JS, Williams TM, Bamberger DL, Fisher TE, Hoffman JM, Hudcosky RJ, MacTough SC, Rooney CS, Saari WS, Thomas CM, et al. Wai JS, et al. Among authors: rooney cs. J Med Chem. 1993 Jan 22;36(2):249-55. doi: 10.1021/jm00054a009. J Med Chem. 1993. PMID: 7678654

9

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues.

Hoffman JM, Smith AM, Rooney CS, Fisher TE, Wai JS, Thomas CM, Bamberger DL, Barnes JL, Williams TM, Jones JH, et al. Hoffman JM, et al. Among authors: rooney cs. J Med Chem. 1993 Apr 16;36(8):953-66. doi: 10.1021/jm00060a002. J Med Chem. 1993. PMID: 7683054

10

Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives.

Rooney CS, Randall WC, Streeter KB, Ziegler C, Cragoe EJ Jr, Schwam H, Michelson SR, Williams HW, Eichler E, Duggan DE, Ulm EH, Noll RM. Rooney CS, et al. J Med Chem. 1983 May;26(5):700-14. doi: 10.1021/jm00359a015. J Med Chem. 1983. PMID: 6341589

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