Shen JK - Search Results

1

Quinoline-3-carboxamide derivatives as potential cholesteryl ester transfer protein inhibitors.

Li WY, Xiong XQ, Zhao DM, Shi YF, Yang ZH, Yu C, Fan PW, Cheng MS, Shen JK. Li WY, et al. Among authors: shen jk. Molecules. 2012 May 9;17(5):5497-507. doi: 10.3390/molecules17055497. Molecules. 2012. PMID: 22572932 Free PMC article.

2

Design, synthesis and SAR of piperidyl-oxadiazoles as 11β-hydroxysteroid dehydrogenase 1 inhibitors.

Xia G, You X, Liu L, Liu H, Wang J, Shi Y, Li P, Xiong B, Liu X, Shen J. Xia G, et al. Eur J Med Chem. 2013 Apr;62:1-10. doi: 10.1016/j.ejmech.2012.12.059. Epub 2013 Jan 10. Eur J Med Chem. 2013. PMID: 23353742

3

Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations.

Yu Z, Ma YC, Ai J, Chen DQ, Zhao DM, Wang X, Chen YL, Geng MY, Xiong B, Cheng MS, Shen JK. Yu Z, et al. Among authors: shen jk. Acta Pharmacol Sin. 2013 Nov;34(11):1475-83. doi: 10.1038/aps.2013.85. Epub 2013 Sep 23. Acta Pharmacol Sin. 2013. PMID: 24056705 Free PMC article.

4

Discovery of 2-Alkyl-1-arylsulfonylprolinamides as 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors.

Yu J, Liu H, Xia G, Liu L, Xu Z, Chen Q, Ma C, Sun X, Xu J, Li H, Li P, Shi Y, Xiong B, Liu X, Shen J. Yu J, et al. ACS Med Chem Lett. 2012 Sep 20;3(10):793-8. doi: 10.1021/ml300144n. eCollection 2012 Oct 11. ACS Med Chem Lett. 2012. PMID: 24900382 Free PMC article.

5

Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors.

Liu TC, Peng X, Ma YC, Ji YC, Chen DQ, Zheng MY, Zhao DM, Cheng MS, Geng MY, Shen JK, Ai J, Xiong B. Liu TC, et al. Among authors: shen jk. Acta Pharmacol Sin. 2016 May;37(5):698-707. doi: 10.1038/aps.2016.11. Epub 2016 Apr 4. Acta Pharmacol Sin. 2016. PMID: 27041462 Free PMC article.

6

Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors.

Zhang Z, Zhao D, Dai Y, Cheng M, Geng M, Shen J, Ma Y, Ai J, Xiong B. Zhang Z, et al. Molecules. 2016 Oct 23;21(10):1407. doi: 10.3390/molecules21101407. Molecules. 2016. PMID: 27782099 Free PMC article.

7

Discovery and Biological Evaluation of a Series of Pyrrolo[2,3-b]pyrazines as Novel FGFR Inhibitors.

Zhang Y, Liu H, Zhang Z, Wang R, Liu T, Wang C, Ma Y, Ai J, Zhao D, Shen J, Xiong B. Zhang Y, et al. Molecules. 2017 Apr 5;22(4):583. doi: 10.3390/molecules22040583. Molecules. 2017. PMID: 28379191 Free PMC article.

8

Preparation of 5'-deoxy-5'-amino-5'-C-methyl adenosine derivatives and their activity against DOT1L.

Liu T, Xie W, Li C, Ren H, Mao Y, Chen G, Cheng M, Zhao D, Shen J, Li J, Zhou Y, Xiong B, Chen YL. Liu T, et al. Bioorg Med Chem Lett. 2017 Nov 15;27(22):4960-4963. doi: 10.1016/j.bmcl.2017.10.019. Epub 2017 Oct 10. Bioorg Med Chem Lett. 2017. PMID: 29050780

9

Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors.

Jiang A, Liu Q, Wang R, Wei P, Dai Y, Wang X, Xu Y, Ma Y, Ai J, Shen J, Ding J, Xiong B. Jiang A, et al. Molecules. 2018 Mar 19;23(3):698. doi: 10.3390/molecules23030698. Molecules. 2018. PMID: 29562726 Free PMC article.

10

Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study.

Wei P, Liu B, Wang R, Gao Y, Li L, Ma Y, Qian Z, Chen Y, Cheng M, Geng M, Shen J, Zhao D, Ai J, Xiong B. Wei P, et al. Acta Pharm Sin B. 2019 Mar;9(2):351-368. doi: 10.1016/j.apsb.2018.12.008. Epub 2018 Dec 26. Acta Pharm Sin B. 2019. PMID: 30972282 Free PMC article.

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