Wu D - Search Results

1

Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen.

Shi T, Bao J, Wang NX, Zheng J, Wu D. Shi T, et al. Among authors: wu d. BMC Chem Biol. 2012 May 14;12:4. doi: 10.1186/1472-6769-12-4. BMC Chem Biol. 2012. PMID: 22584113 Free PMC article.

2

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled.

Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J. Wong HC, et al. Among authors: wu d. Mol Cell. 2003 Nov;12(5):1251-60. doi: 10.1016/s1097-2765(03)00427-1. Mol Cell. 2003. PMID: 14636582 Free PMC article.

3

Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway.

Maye P, Zheng J, Li L, Wu D. Maye P, et al. Among authors: wu d. J Biol Chem. 2004 Jun 4;279(23):24659-65. doi: 10.1074/jbc.M311724200. Epub 2004 Apr 2. J Biol Chem. 2004. PMID: 15067007 Free article.

4

The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd.

Zhang Y, Wang Y, Li X, Zhang J, Mao J, Li Z, Zheng J, Li L, Harris S, Wu D. Zhang Y, et al. Among authors: wu d. Mol Cell Biol. 2004 Jun;24(11):4677-84. doi: 10.1128/MCB.24.11.4677-4684.2004. Mol Cell Biol. 2004. PMID: 15143163 Free PMC article.

5

Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism.

Wang K, Zhang Y, Li X, Chen L, Wang H, Wu J, Zheng J, Wu D. Wang K, et al. Among authors: wu d, wu j. J Biol Chem. 2008 Aug 22;283(34):23371-5. doi: 10.1074/jbc.M802376200. Epub 2008 May 23. J Biol Chem. 2008. PMID: 18502762 Free PMC article.

6

Structural insight into the mechanisms of Wnt signaling antagonism by Dkk.

Chen L, Wang K, Shao Y, Huang J, Li X, Shan J, Wu D, Zheng JJ. Chen L, et al. Among authors: wu d. J Biol Chem. 2008 Aug 22;283(34):23364-70. doi: 10.1074/jbc.M802375200. Epub 2008 Jun 3. J Biol Chem. 2008. PMID: 18524778 Free PMC article.

7

Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein.

Lee HJ, Finkelstein D, Li X, Wu D, Shi DL, Zheng JJ. Lee HJ, et al. Among authors: wu d. J Biol Chem. 2010 Dec 31;285(53):41549-56. doi: 10.1074/jbc.M110.193383. Epub 2010 Nov 2. J Biol Chem. 2010. PMID: 21044957 Free PMC article.

8

The structural basis of DKK-mediated inhibition of Wnt/LRP signaling.

Bao J, Zheng JJ, Wu D. Bao J, et al. Among authors: wu d. Sci Signal. 2012 May 15;5(224):pe22. doi: 10.1126/scisignal.2003028. Sci Signal. 2012. PMID: 22589387 Free PMC article.

9

Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism.

Li X, Shan J, Chang W, Kim I, Bao J, Lee HJ, Zhang X, Samuel VT, Shulman GI, Liu D, Zheng JJ, Wu D. Li X, et al. Among authors: wu d. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11402-7. doi: 10.1073/pnas.1205015109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733757 Free PMC article.

10

Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled.

Lee HJ, Bao J, Miller A, Zhang C, Wu J, Baday YC, Guibao C, Li L, Wu D, Zheng JJ. Lee HJ, et al. Among authors: wu d, wu j. J Biol Chem. 2015 Dec 18;290(51):30596-606. doi: 10.1074/jbc.M115.673202. Epub 2015 Oct 26. J Biol Chem. 2015. PMID: 26504084 Free PMC article.

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