Ochi T - Search Results

1

Spatial and temporal organization of multi-protein assemblies: achieving sensitive control in information-rich cell-regulatory systems.

Bolanos-Garcia VM, Wu Q, Ochi T, Chirgadze DY, Sibanda BL, Blundell TL. Bolanos-Garcia VM, et al. Among authors: ochi t. Philos Trans A Math Phys Eng Sci. 2012 Jun 28;370(1969):3023-39. doi: 10.1098/rsta.2011.0268. Philos Trans A Math Phys Eng Sci. 2012. PMID: 22615474

2

The spatial organization of non-homologous end joining: from bridging to end joining.

Ochi T, Wu Q, Blundell TL. Ochi T, et al. DNA Repair (Amst). 2014 May;17(100):98-109. doi: 10.1016/j.dnarep.2014.02.010. Epub 2014 Mar 11. DNA Repair (Amst). 2014. PMID: 24636752 Free PMC article.

3

Perspectives on protein crystallisation.

Ochi T, Bolanos-Garcia VM, Stojanoff V, Moreno A. Ochi T, et al. Prog Biophys Mol Biol. 2009 Nov;101(1-3):56-63. doi: 10.1016/j.pbiomolbio.2009.12.001. Epub 2009 Dec 11. Prog Biophys Mol Biol. 2009. PMID: 20005246 Review.

4

Structural biology of DNA repair: spatial organisation of the multicomponent complexes of nonhomologous end joining.

Ochi T, Sibanda BL, Wu Q, Chirgadze DY, Bolanos-Garcia VM, Blundell TL. Ochi T, et al. J Nucleic Acids. 2010 Aug 25;2010:621695. doi: 10.4061/2010/621695. J Nucleic Acids. 2010. PMID: 20862368 Free PMC article.

5

Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions.

Wu Q, Ochi T, Matak-Vinkovic D, Robinson CV, Chirgadze DY, Blundell TL. Wu Q, et al. Among authors: ochi t. Biochem Soc Trans. 2011 Oct;39(5):1387-92, suppl 2 p following 1392. doi: 10.1042/BST0391387. Biochem Soc Trans. 2011. PMID: 21936820

6

Structural insights into the role of domain flexibility in human DNA ligase IV.

Ochi T, Wu Q, Chirgadze DY, Grossmann JG, Bolanos-Garcia VM, Blundell TL. Ochi T, et al. Structure. 2012 Jul 3;20(7):1212-22. doi: 10.1016/j.str.2012.04.012. Epub 2012 May 31. Structure. 2012. PMID: 22658747 Free PMC article.

7

Structure of the catalytic region of DNA ligase IV in complex with an Artemis fragment sheds light on double-strand break repair.

Ochi T, Gu X, Blundell TL. Ochi T, et al. Structure. 2013 Apr 2;21(4):672-9. doi: 10.1016/j.str.2013.02.014. Epub 2013 Mar 21. Structure. 2013. PMID: 23523427 Free PMC article.

8

Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways.

Wu Q, Liang S, Ochi T, Chirgadze DY, Huiskonen JT, Blundell TL. Wu Q, et al. Among authors: ochi t. Prog Biophys Mol Biol. 2019 Oct;147:26-32. doi: 10.1016/j.pbiomolbio.2019.03.007. Epub 2019 Apr 20. Prog Biophys Mol Biol. 2019. PMID: 31014919 Free article. Review.

9

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.

Ochi T, Blackford AN, Coates J, Jhujh S, Mehmood S, Tamura N, Travers J, Wu Q, Draviam VM, Robinson CV, Blundell TL, Jackson SP. Ochi T, et al. Science. 2015 Jan 9;347(6218):185-188. doi: 10.1126/science.1261971. Science. 2015. PMID: 25574025 Free PMC article.

10

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.

Wu Q, Paul A, Su D, Mehmood S, Foo TK, Ochi T, Bunting EL, Xia B, Robinson CV, Wang B, Blundell TL. Wu Q, et al. Among authors: ochi t. Mol Cell. 2016 Feb 4;61(3):434-448. doi: 10.1016/j.molcel.2015.12.017. Epub 2016 Jan 14. Mol Cell. 2016. PMID: 26778126 Free PMC article.

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