Bertolotti A - Search Results

1

Sustained translational repression by eIF2α-P mediates prion neurodegeneration.

Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, Halliday M, Morgan J, Dinsdale D, Ortori CA, Barrett DA, Tsaytler P, Bertolotti A, Willis AE, Bushell M, Mallucci GR. Moreno JA, et al. Among authors: bertolotti a. Nature. 2012 May 6;485(7399):507-11. doi: 10.1038/nature11058. Nature. 2012. PMID: 22622579 Free PMC article.

2

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis.

Tsaytler P, Harding HP, Ron D, Bertolotti A. Tsaytler P, et al. Among authors: bertolotti a. Science. 2011 Apr 1;332(6025):91-4. doi: 10.1126/science.1201396. Epub 2011 Mar 3. Science. 2011. PMID: 21385720

3

Propagation of the prion phenomenon: beyond the seeding principle.

Münch C, Bertolotti A. Münch C, et al. Among authors: bertolotti a. J Mol Biol. 2012 Aug 24;421(4-5):491-8. doi: 10.1016/j.jmb.2011.12.061. Epub 2012 Jan 5. J Mol Biol. 2012. PMID: 22245492 Review.

4

Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention.

Tsaytler P, Bertolotti A. Tsaytler P, et al. Among authors: bertolotti a. FEBS J. 2013 Jan;280(2):766-70. doi: 10.1111/j.1742-4658.2012.08535.x. Epub 2012 Mar 14. FEBS J. 2013. PMID: 22340633 Free article. Review.

5

qMotor, a set of rules for sensitive, robust and quantitative measurement of motor performance in mice.

Luh LM, Das I, Bertolotti A. Luh LM, et al. Among authors: bertolotti a. Nat Protoc. 2017 Jul;12(7):1451-1457. doi: 10.1038/nprot.2017.062. Epub 2016 Jun 29. Nat Protoc. 2017. PMID: 28686587 Free PMC article.

6

Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors.

Carrara M, Sigurdardottir A, Bertolotti A. Carrara M, et al. Among authors: bertolotti a. Nat Struct Mol Biol. 2017 Sep;24(9):708-716. doi: 10.1038/nsmb.3443. Epub 2017 Jul 31. Nat Struct Mol Biol. 2017. PMID: 28759048 Free PMC article.

7

An Overview of Methods for Detecting eIF2α Phosphorylation and the Integrated Stress Response.

Krzyzosiak A, Pitera AP, Bertolotti A. Krzyzosiak A, et al. Among authors: bertolotti a. Methods Mol Biol. 2022;2428:3-18. doi: 10.1007/978-1-0716-1975-9_1. Methods Mol Biol. 2022. PMID: 35171470 Review.

8

Activation of the integrated stress response by inhibitors of its kinases.

Szaruga M, Janssen DA, de Miguel C, Hodgson G, Fatalska A, Pitera AP, Andreeva A, Bertolotti A. Szaruga M, et al. Among authors: bertolotti a. Nat Commun. 2023 Sep 8;14(1):5535. doi: 10.1038/s41467-023-40823-8. Nat Commun. 2023. PMID: 37684277 Free PMC article.

9

Regulation of proteasome assembly and activity in health and disease.

Rousseau A, Bertolotti A. Rousseau A, et al. Among authors: bertolotti a. Nat Rev Mol Cell Biol. 2018 Nov;19(11):697-712. doi: 10.1038/s41580-018-0040-z. Nat Rev Mol Cell Biol. 2018. PMID: 30065390 Review.

10

Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation.

Schneider K, Nelson GM, Watson JL, Morf J, Dalglish M, Luh LM, Weber A, Bertolotti A. Schneider K, et al. Among authors: bertolotti a. Cell Rep. 2020 Sep 15;32(11):108154. doi: 10.1016/j.celrep.2020.108154. Cell Rep. 2020. PMID: 32937139 Free PMC article.

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