McDonough MA - Search Results

1

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

Demetriades M, Leung IK, Chowdhury R, Chan MC, McDonough MA, Yeoh KK, Tian YM, Claridge TD, Ratcliffe PJ, Woon EC, Schofield CJ. Demetriades M, et al. Among authors: mcdonough ma. Angew Chem Int Ed Engl. 2012 Jul 2;51(27):6672-5. doi: 10.1002/anie.201202000. Epub 2012 May 25. Angew Chem Int Ed Engl. 2012. PMID: 22639232 No abstract available.

2

New structural insights into the inhibition of serine proteases by cyclic peptides from bacteria.

McDonough MA, Schofield CJ. McDonough MA, et al. Chem Biol. 2003 Oct;10(10):898-900. doi: 10.1016/j.chembiol.2003.10.002. Chem Biol. 2003. PMID: 14583255 No abstract available.

3

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.

Lancaster DE, McNeill LA, McDonough MA, Aplin RT, Hewitson KS, Pugh CW, Ratcliffe PJ, Schofield CJ. Lancaster DE, et al. Among authors: mcdonough ma. Biochem J. 2004 Nov 1;383(Pt. 3):429-37. doi: 10.1042/BJ20040735. Biochem J. 2004. PMID: 15239670 Free PMC article.

4

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.

Lancaster DE, McDonough MA, Schofield CJ. Lancaster DE, et al. Among authors: mcdonough ma. Biochem Soc Trans. 2004 Dec;32(Pt 6):943-5. doi: 10.1042/BST0320943. Biochem Soc Trans. 2004. PMID: 15506931 Review.

5

OS-9: another piece in the HIF complex story.

Flashman E, McDonough MA, Schofield CJ. Flashman E, et al. Among authors: mcdonough ma. Mol Cell. 2005 Feb 18;17(4):472-3. doi: 10.1016/j.molcel.2005.02.001. Mol Cell. 2005. PMID: 15721249 Free article. Review.

6

Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

Hewitson KS, Granatino N, Welford RW, McDonough MA, Schofield CJ. Hewitson KS, et al. Among authors: mcdonough ma. Philos Trans A Math Phys Eng Sci. 2005 Apr 15;363(1829):807-28; discussion 1035-40. doi: 10.1098/rsta.2004.1540. Philos Trans A Math Phys Eng Sci. 2005. PMID: 15901537 Review.

7

Selective inhibition of factor inhibiting hypoxia-inducible factor.

McDonough MA, McNeill LA, Tilliet M, Papamicaël CA, Chen QY, Banerji B, Hewitson KS, Schofield CJ. McDonough MA, et al. J Am Chem Soc. 2005 Jun 1;127(21):7680-1. doi: 10.1021/ja050841b. J Am Chem Soc. 2005. PMID: 15913349

8

Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.

Sleeman MC, Sorensen JL, Batchelar ET, McDonough MA, Schofield CJ. Sleeman MC, et al. Among authors: mcdonough ma. J Biol Chem. 2005 Oct 14;280(41):34956-65. doi: 10.1074/jbc.M507196200. Epub 2005 Aug 11. J Biol Chem. 2005. PMID: 16096274 Free article.

9

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ. McDonough MA, et al. J Biol Chem. 2005 Dec 9;280(49):41101-10. doi: 10.1074/jbc.M507528200. Epub 2005 Sep 25. J Biol Chem. 2005. PMID: 16186124 Free article.

10

The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids.

Banerji B, Conejo-Garcia A, McNeill LA, McDonough MA, Buck MR, Hewitson KS, Oldham NJ, Schofield CJ. Banerji B, et al. Among authors: mcdonough ma. Chem Commun (Camb). 2005 Nov 21;(43):5438-40. doi: 10.1039/b510707e. Epub 2005 Oct 4. Chem Commun (Camb). 2005. PMID: 16261239

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