Hwang HS - Search Results

1

Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia.

Schober T, Huke S, Venkataraman R, Gryshchenko O, Kryshtal D, Hwang HS, Baudenbacher FJ, Knollmann BC. Schober T, et al. Among authors: hwang hs. Circ Res. 2012 Jul 6;111(2):170-9. doi: 10.1161/CIRCRESAHA.112.270041. Epub 2012 May 29. Circ Res. 2012. PMID: 22647877 Free PMC article.

2

Focal energy deprivation underlies arrhythmia susceptibility in mice with calcium-sensitized myofilaments.

Huke S, Venkataraman R, Faggioni M, Bennuri S, Hwang HS, Baudenbacher F, Knollmann BC. Huke S, et al. Among authors: hwang hs. Circ Res. 2013 May 10;112(10):1334-44. doi: 10.1161/CIRCRESAHA.113.301055. Epub 2013 Mar 26. Circ Res. 2013. PMID: 23532597 Free PMC article.

3

Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients.

Faggioni M, Hwang HS, van der Werf C, Nederend I, Kannankeril PJ, Wilde AA, Knollmann BC. Faggioni M, et al. Among authors: hwang hs. Circ Res. 2013 Feb 15;112(4):689-97. doi: 10.1161/CIRCRESAHA.111.300076. Epub 2013 Jan 7. Circ Res. 2013. PMID: 23295832 Free PMC article.

4

Myofilament calcium de-sensitization and contractile uncoupling prevent pause-triggered ventricular tachycardia in mouse hearts with chronic myocardial infarction.

Venkataraman R, Baldo MP, Hwang HS, Veltri T, Pinto JR, Baudenbacher FJ, Knollmann BC. Venkataraman R, et al. Among authors: hwang hs. J Mol Cell Cardiol. 2013 Jul;60:8-15. doi: 10.1016/j.yjmcc.2013.03.022. Epub 2013 Apr 6. J Mol Cell Cardiol. 2013. PMID: 23570978 Free PMC article.

5

Suppression of spontaneous ca elevations prevents atrial fibrillation in calsequestrin 2-null hearts.

Faggioni M, Savio-Galimberti E, Venkataraman R, Hwang HS, Kannankeril PJ, Darbar D, Knollmann BC. Faggioni M, et al. Among authors: hwang hs. Circ Arrhythm Electrophysiol. 2014 Apr;7(2):313-20. doi: 10.1161/CIRCEP.113.000994. Epub 2014 Feb 3. Circ Arrhythm Electrophysiol. 2014. PMID: 24493699 Free PMC article.

6

Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants.

Hwang HS, Nitu FR, Yang Y, Walweel K, Pereira L, Johnson CN, Faggioni M, Chazin WJ, Laver D, George AL Jr, Cornea RL, Bers DM, Knollmann BC. Hwang HS, et al. Circ Res. 2014 Mar 28;114(7):1114-24. doi: 10.1161/CIRCRESAHA.114.303391. Epub 2014 Feb 21. Circ Res. 2014. PMID: 24563457 Free PMC article.

7

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.

Watanabe H, Chopra N, Laver D, Hwang HS, Davies SS, Roach DE, Duff HJ, Roden DM, Wilde AA, Knollmann BC. Watanabe H, et al. Among authors: hwang hs. Nat Med. 2009 Apr;15(4):380-3. doi: 10.1038/nm.1942. Epub 2009 Mar 29. Nat Med. 2009. PMID: 19330009 Free PMC article.

8

Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

Hwang HS, Hasdemir C, Laver D, Mehra D, Turhan K, Faggioni M, Yin H, Knollmann BC. Hwang HS, et al. Circ Arrhythm Electrophysiol. 2011 Apr;4(2):128-35. doi: 10.1161/CIRCEP.110.959916. Epub 2011 Jan 26. Circ Arrhythm Electrophysiol. 2011. PMID: 21270101 Free PMC article.

9

Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.

Hwang HS, Kryshtal DO, Feaster TK, Sánchez-Freire V, Zhang J, Kamp TJ, Hong CC, Wu JC, Knollmann BC. Hwang HS, et al. J Mol Cell Cardiol. 2015 Aug;85:79-88. doi: 10.1016/j.yjmcc.2015.05.003. Epub 2015 May 14. J Mol Cell Cardiol. 2015. PMID: 25982839 Free PMC article.

10

Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes to understand and test cardiac calcium handling: A glass half full.

Hwang HS, Kryshtal DO, Feaster TK, Sánchez-Freire V, Zhang J, Kamp TJ, Hong CC, Wu JC, Knollmann BC. Hwang HS, et al. J Mol Cell Cardiol. 2015 Dec;89(Pt B):379-80. doi: 10.1016/j.yjmcc.2015.10.021. J Mol Cell Cardiol. 2015. PMID: 26695095 No abstract available.

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