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Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Fraser P, Westaway D, St George-Hyslop PH, Szabo P, Relkin NR, Buxbaum JD, Glabe CG, Protter AA, Martins RN, Ehrlich ME, Petsko GA, Yue Z, Gandy S. Steele JW, et al. Among authors: lachenmayer ml. Mol Psychiatry. 2013 Aug;18(8):889-97. doi: 10.1038/mp.2012.106. Epub 2012 Jul 31. Mol Psychiatry. 2013. PMID: 22850627 Free PMC article.
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S. Steele JW, et al. Among authors: lachenmayer ml. Mol Psychiatry. 2013 Aug;18(8):882-8. doi: 10.1038/mp.2012.115. Epub 2012 Aug 7. Mol Psychiatry. 2013. PMID: 22869031 Free PMC article.
Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.
Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN. Bharadwaj PR, et al. Among authors: lachenmayer ml. J Alzheimers Dis. 2012;32(4):949-67. doi: 10.3233/JAD-2012-120178. J Alzheimers Dis. 2012. PMID: 22903131 Free PMC article.
Morphometric changes of sensorimotor structures in focal dystonia.
Obermann M, Yaldizli O, De Greiff A, Lachenmayer ML, Buhl AR, Tumczak F, Gizewski ER, Diener HC, Maschke M. Obermann M, et al. Among authors: lachenmayer ml. Mov Disord. 2007 Jun 15;22(8):1117-23. doi: 10.1002/mds.21495. Mov Disord. 2007. PMID: 17443700
Apathy in Parkinson's disease with REM sleep behavior disorder.
Bargiotas P, Ntafouli M, Lachenmayer ML, Krack P, Schüpbach WMM, Bassetti CLA. Bargiotas P, et al. Among authors: lachenmayer ml. J Neurol Sci. 2019 Apr 15;399:194-198. doi: 10.1016/j.jns.2019.02.028. Epub 2019 Feb 20. J Neurol Sci. 2019. PMID: 30826716
30 results