Annaert W - Search Results

1

Peptides based on the presenilin-APP binding domain inhibit APP processing and Aβ production through interfering with the APP transmembrane domain.

Esselens C, Sannerud R, Gallardo R, Baert V, Kaden D, Serneels L, De Strooper B, Rousseau F, Multhaup G, Schymkowitz J, Langedijk JP, Annaert W. Esselens C, et al. Among authors: annaert w. FASEB J. 2012 Sep;26(9):3765-78. doi: 10.1096/fj.11-201368. Epub 2012 Jun 1. FASEB J. 2012. PMID: 22661005

2

Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons.

Annaert WG, Levesque L, Craessaerts K, Dierinck I, Snellings G, Westaway D, George-Hyslop PS, Cordell B, Fraser P, De Strooper B. Annaert WG, et al. J Cell Biol. 1999 Oct 18;147(2):277-94. doi: 10.1083/jcb.147.2.277. J Cell Biol. 1999. PMID: 10525535 Free PMC article.

3

Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins.

Annaert WG, Esselens C, Baert V, Boeve C, Snellings G, Cupers P, Craessaerts K, De Strooper B. Annaert WG, et al. Neuron. 2001 Nov 20;32(4):579-89. doi: 10.1016/s0896-6273(01)00512-8. Neuron. 2001. PMID: 11719200 Free article.

4

FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction.

Flood DG, Reaume AG, Dorfman KS, Lin YG, Lang DM, Trusko SP, Savage MJ, Annaert WG, De Strooper B, Siman R, Scott RW. Flood DG, et al. Among authors: annaert wg. Neurobiol Aging. 2002 May-Jun;23(3):335-48. doi: 10.1016/s0197-4580(01)00330-x. Neurobiol Aging. 2002. PMID: 11959395

5

No endogenous A beta production in presenilin-deficient fibroblasts.

Nyabi O, Pype S, Mercken M, Herreman A, Saftig P, Craessaerts K, Serneels L, Annaert W, De Strooper B. Nyabi O, et al. Among authors: annaert w. Nat Cell Biol. 2002 Jul;4(7):E164; author reply E165-6. doi: 10.1038/ncb0702-e164a. Nat Cell Biol. 2002. PMID: 12105423 No abstract available.

6

A cell biological perspective on Alzheimer's disease.

Annaert W, De Strooper B. Annaert W, et al. Annu Rev Cell Dev Biol. 2002;18:25-51. doi: 10.1146/annurev.cellbio.18.020402.142302. Epub 2002 Apr 2. Annu Rev Cell Dev Biol. 2002. PMID: 12142279 Review.

7

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.

Hartmann D, de Strooper B, Serneels L, Craessaerts K, Herreman A, Annaert W, Umans L, Lübke T, Lena Illert A, von Figura K, Saftig P. Hartmann D, et al. Among authors: annaert w. Hum Mol Genet. 2002 Oct 1;11(21):2615-24. doi: 10.1093/hmg/11.21.2615. Hum Mol Genet. 2002. PMID: 12354787

8

gamma-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation.

Herreman A, Van Gassen G, Bentahir M, Nyabi O, Craessaerts K, Mueller U, Annaert W, De Strooper B. Herreman A, et al. Among authors: annaert w. J Cell Sci. 2003 Mar 15;116(Pt 6):1127-36. doi: 10.1242/jcs.00292. J Cell Sci. 2003. PMID: 12584255 Free article.

9

Amyloid, presenilins, and Alzheimer's disease.

Van Gassen G, Annaert W. Van Gassen G, et al. Among authors: annaert w. Neuroscientist. 2003 Apr;9(2):117-26. doi: 10.1177/1073858403252227. Neuroscientist. 2003. PMID: 12708616 Review.

10

Gene profiling of hippocampal neuronal culture.

Dabrowski M, Aerts S, Van Hummelen P, Craessaerts K, De Moor B, Annaert W, Moreau Y, De Strooper B. Dabrowski M, et al. Among authors: annaert w. J Neurochem. 2003 Jun;85(5):1279-88. doi: 10.1046/j.1471-4159.2003.01753.x. J Neurochem. 2003. PMID: 12753086 Free article.

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