Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor.
Ye Q, Shvartsbart A, Li Z, Gan P, Policarpo RL, Qi C, Roach JJ, Zhu W, McCammant MS, Hu B, Li G, Yin H, Carlsen P, Hoang G, Zhao L, Susick R, Zhang F, Lai CT, Allali Hassani A, Epling LB, Gallion A, Kurzeja-Lipinski K, Gallagher K, Roman V, Farren MR, Kong W, Deller MC, Zhang G, Covington M, Diamond S, Kim S, Yao W, Sokolsky A, Wang X.
Ye Q, et al. Among authors: qi c.
J Med Chem. 2025 Jan 8. doi: 10.1021/acs.jmedchem.4c02662. Online ahead of print.
J Med Chem. 2025.
PMID: 39772605