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Page 1
Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias.
Zorko NA, Bernot KM, Whitman SP, Siebenaler RF, Ahmed EH, Marcucci GG, Yanes DA, McConnell KK, Mao C, Kalu C, Zhang X, Jarjoura D, Dorrance AM, Heerema NA, Lee BH, Huang G, Marcucci G, Caligiuri MA. Zorko NA, et al. Among authors: mcconnell kk. Blood. 2012 Aug 2;120(5):1130-6. doi: 10.1182/blood-2012-03-415067. Epub 2012 Jun 6. Blood. 2012. PMID: 22674806 Free PMC article.
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
Trotta R, Chen L, Costinean S, Josyula S, Mundy-Bosse BL, Ciarlariello D, Mao C, Briercheck EL, McConnell KK, Mishra A, Yu L, Croce CM, Caligiuri MA. Trotta R, et al. Among authors: mcconnell kk. Blood. 2013 Apr 18;121(16):3126-34. doi: 10.1182/blood-2012-12-467597. Epub 2013 Feb 19. Blood. 2013. PMID: 23422749 Free PMC article.
Toward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML.
Bernot KM, Siebenaler RF, Whitman SP, Zorko NA, Marcucci GG, Santhanam R, Ahmed EH, Ngangana M, McConnell KK, Nemer JS, Brook DL, Kulp SK, Chen CS, Frankhouser D, Yan P, Bundschuh R, Zhang X, Dorrance AM, Dickerson KE, Jarjoura D, Blum W, Marcucci G, Caligiuri MA. Bernot KM, et al. Among authors: mcconnell kk. Leukemia. 2013 Dec;27(12):2379-82. doi: 10.1038/leu.2013.147. Epub 2013 May 10. Leukemia. 2013. PMID: 23660685 Free PMC article. No abstract available.
Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.
Bernot KM, Nemer JS, Santhanam R, Liu S, Zorko NA, Whitman SP, Dickerson KE, Zhang M, Yang X, McConnell KK, Ahmed EH, Muñoz MR, Siebenaler RF, Marcucci GG, Mundy-Bosse BL, Brook DL, Garman S, Dorrance AM, Zhang X, Zhang J, Lee RJ, Blum W, Caligiuri MA, Marcucci G. Bernot KM, et al. Among authors: mcconnell kk. Blood. 2013 Nov 28;122(23):3778-83. doi: 10.1182/blood-2013-06-507426. Epub 2013 Oct 1. Blood. 2013. PMID: 24085765 Free PMC article.
MicroRNA-29b mediates altered innate immune development in acute leukemia.
Mundy-Bosse BL, Scoville SD, Chen L, McConnell K, Mao HC, Ahmed EH, Zorko N, Harvey S, Cole J, Zhang X, Costinean S, Croce CM, Larkin K, Byrd JC, Vasu S, Blum W, Yu J, Freud AG, Caligiuri MA. Mundy-Bosse BL, et al. J Clin Invest. 2016 Dec 1;126(12):4404-4416. doi: 10.1172/JCI85413. Epub 2016 Oct 24. J Clin Invest. 2016. PMID: 27775550 Free PMC article.
Human AML activates the aryl hydrocarbon receptor pathway to impair NK cell development and function.
Scoville SD, Nalin AP, Chen L, Chen L, Zhang MH, McConnell K, Beceiro Casas S, Ernst G, Traboulsi AA, Hashi N, Williams M, Zhang X, Hughes T, Mishra A, Benson DM, Saultz JN, Yu J, Freud AG, Caligiuri MA, Mundy-Bosse BL. Scoville SD, et al. Blood. 2018 Oct 25;132(17):1792-1804. doi: 10.1182/blood-2018-03-838474. Epub 2018 Aug 29. Blood. 2018. PMID: 30158248 Free PMC article.
Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma.
Mundy-Bosse BL, Weigel C, Wu YZ, Abdelbaky S, Youssef Y, Casas SB, Polley N, Ernst G, Young KA, McConnell KK, Nalin AP, Wu KG, Broughton M, Lordo MR, Altynova E, Hegewisch-Solloa E, Enriquez-Vera DY, Dueñas D, Barrionuevo C, Yu SC, Saleem A, Suarez CJ, Briercheck EL, Molina-Kirsch H, Loughran TP, Weichenhan D, Plass C, Reneau JC, Mace EM, Gamboa FV, Weinstock DM, Natkunam Y, Caligiuri MA, Mishra A, Porcu P, Baiocchi RA, Brammer JE, Freud AG, Oakes CC. Mundy-Bosse BL, et al. Among authors: mcconnell kk. Blood Cancer Discov. 2022 Mar 1;3(2):154-169. doi: 10.1158/2643-3230.BCD-21-0098. Blood Cancer Discov. 2022. PMID: 35247900 Free PMC article.
Preclinical evaluation of anti-CD38 therapy in mature T-cell neoplasms.
Isabelle C, Johnson WT, McConnell K, Vogel A, Brammer JE, Boles A, Keller R, Sindaco P, Nisenfeld L, Uppal G, Nikbakht N, Calabretta B, Porazzi P, Gong J, Chakravarti N, Porcu P, Mishra A. Isabelle C, et al. Blood Adv. 2023 Jul 25;7(14):3637-3641. doi: 10.1182/bloodadvances.2023009807. Blood Adv. 2023. PMID: 36989058 Free PMC article. No abstract available.
19 results