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Page 1
Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22.
Cicek MS, Cunningham JM, Fridley BL, Serie DJ, Bamlet WR, Diergaarde B, Haile RW, Le Marchand L, Krontiris TG, Younghusband HB, Gallinger S, Newcomb PA, Hopper JL, Jenkins MA, Casey G, Schumacher F, Chen Z, DeRycke MS, Templeton AS, Winship I, Green RC, Green JS, Macrae FA, Parry S, Young GP, Young JP, Buchanan D, Thomas DC, Bishop DT, Lindor NM, Thibodeau SN, Potter JD, Goode EL; Colon CFR. Cicek MS, et al. Among authors: younghusband hb. PLoS One. 2012;7(5):e38175. doi: 10.1371/journal.pone.0038175. Epub 2012 May 31. PLoS One. 2012. PMID: 22675446 Free PMC article.
Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, Hudson TJ, McLaughlin JR, Green RC, Zanke BW, Newcomb PA, Paterson AD, Bapat B. Mrkonjic M, et al. Among authors: younghusband hb. PLoS One. 2010 Oct 13;5(10):e13314. doi: 10.1371/journal.pone.0013314. PLoS One. 2010. PMID: 20967208 Free PMC article.
The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease.
Woods MO, Younghusband HB, Parfrey PS, Gallinger S, McLaughlin J, Dicks E, Stuckless S, Pollett A, Bapat B, Mrkonjic M, de la Chapelle A, Clendenning M, Thibodeau SN, Simms M, Dohey A, Williams P, Robb D, Searle C, Green JS, Green RC. Woods MO, et al. Among authors: younghusband hb. Gut. 2010 Oct;59(10):1369-77. doi: 10.1136/gut.2010.208462. Epub 2010 Aug 3. Gut. 2010. PMID: 20682701 Free PMC article.
Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status.
Campbell PT, Jacobs ET, Ulrich CM, Figueiredo JC, Poynter JN, McLaughlin JR, Haile RW, Jacobs EJ, Newcomb PA, Potter JD, Le Marchand L, Green RC, Parfrey P, Younghusband HB, Cotterchio M, Gallinger S, Jenkins MA, Hopper JL, Baron JA, Thibodeau SN, Lindor NM, Limburg PJ, Martínez ME; Colon Cancer Family Registry. Campbell PT, et al. Among authors: younghusband hb. J Natl Cancer Inst. 2010 Mar 17;102(6):391-400. doi: 10.1093/jnci/djq011. Epub 2010 Mar 5. J Natl Cancer Inst. 2010. PMID: 20208017 Free PMC article.
Increased cancer predisposition in family members of colorectal cancer patients harboring the p.V600E BRAF mutation: a population-based study.
Wish TA, Hyde AJ, Parfrey PS, Green JS, Younghusband HB, Simms MI, Fontaine DG, Dicks EL, Stuckless SN, Gallinger S, McLaughlin JR, Woods MO, Green RC. Wish TA, et al. Among authors: younghusband hb. Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1831-9. doi: 10.1158/1055-9965.EPI-10-0055. Epub 2010 Jun 22. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20570909
High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes.
Woods MO, Hyde AJ, Curtis FK, Stuckless S, Green JS, Pollett AF, Robb JD, Green RC, Croitoru ME, Careen A, Chaulk JA, Jegathesan J, McLaughlin JR, Gallinger SS, Younghusband HB, Bapat BV, Parfrey PS. Woods MO, et al. Among authors: younghusband hb. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6853-61. doi: 10.1158/1078-0432.CCR-05-0726. Clin Cancer Res. 2005. PMID: 16203774
MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer.
Mrkonjic M, Raptis S, Green RC, Monga N, Daftary D, Dicks E, Younghusband HB, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. Mrkonjic M, et al. Among authors: younghusband hb. Carcinogenesis. 2007 Dec;28(12):2575-80. doi: 10.1093/carcin/bgm229. Epub 2007 Oct 17. Carcinogenesis. 2007. PMID: 17942459
46 results