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Page 1
Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.
Ceccaldi R, Parmar K, Mouly E, Delord M, Kim JM, Regairaz M, Pla M, Vasquez N, Zhang QS, Pondarre C, Peffault de Latour R, Gluckman E, Cavazzana-Calvo M, Leblanc T, Larghero J, Grompe M, Socié G, D'Andrea AD, Soulier J. Ceccaldi R, et al. Among authors: pla m. Cell Stem Cell. 2012 Jul 6;11(1):36-49. doi: 10.1016/j.stem.2012.05.013. Epub 2012 Jun 7. Cell Stem Cell. 2012. PMID: 22683204 Free PMC article.
Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.
Domenech C, Maillard L, Rousseau A, Guidez F, Petit L, Pla M, Clay D, Guimiot F, Sanfilippo S, Jacques S, de la Grange P, Robil N, Soulier J, Souyri M. Domenech C, et al. Among authors: pla m. Stem Cell Reports. 2018 Nov 13;11(5):1075-1091. doi: 10.1016/j.stemcr.2018.10.001. Epub 2018 Oct 25. Stem Cell Reports. 2018. PMID: 30449320 Free PMC article.
Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.
Djeghloul D, Kuranda K, Kuzniak I, Barbieri D, Naguibneva I, Choisy C, Bories JC, Dosquet C, Pla M, Vanneaux V, Socié G, Porteu F, Garrick D, Goodhardt M. Djeghloul D, et al. Among authors: pla m. Stem Cell Reports. 2016 Jun 14;6(6):970-984. doi: 10.1016/j.stemcr.2016.05.007. Stem Cell Reports. 2016. PMID: 27304919 Free PMC article.
Dynamics of human prothymocytes and xenogeneic thymopoiesis in hematopoietic stem cell-engrafted nonobese diabetic-SCID/IL-2rγnull mice.
Parietti V, Nelson E, Telliam G, Le Noir S, Pla M, Delord M, Vanneaux V, Mohtashami M, Macintyre EA, Gluckman JC, Asnafi V, Zúñiga-Pflücker JC, Larghero J, Canque B. Parietti V, et al. Among authors: pla m. J Immunol. 2012 Aug 15;189(4):1648-60. doi: 10.4049/jimmunol.1201251. Epub 2012 Jul 13. J Immunol. 2012. PMID: 22798679
Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation.
Gachet S, El-Chaar T, Avran D, Genesca E, Catez F, Quentin S, Delord M, Thérizols G, Briot D, Meunier G, Hernandez L, Pla M, Smits WK, Buijs-Gladdines JG, Van Loocke W, Menschaert G, André-Schmutz I, Taghon T, Van Vlierberghe P, Meijerink JP, Baruchel A, Dombret H, Clappier E, Diaz JJ, Gazin C, de Thé H, Sigaux F, Soulier J. Gachet S, et al. Among authors: pla m. Cancer Discov. 2018 Dec;8(12):1614-1631. doi: 10.1158/2159-8290.CD-17-0831. Epub 2018 Sep 28. Cancer Discov. 2018. PMID: 30266814
AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.
Parcelier A, Maharzi N, Delord M, Robledo-Sarmiento M, Nelson E, Belakhdar-Mekid H, Pla M, Kuranda K, Parietti V, Goodhardt M, Legrand N, Bernstein ID, Gluckman JC, Sigaux F, Canque B. Parcelier A, et al. Among authors: pla m. Blood. 2011 Aug 18;118(7):1784-96. doi: 10.1182/blood-2011-01-333179. Epub 2011 Jun 28. Blood. 2011. PMID: 21715312 Free PMC article.
Frequent antibody production against RARalpha in both APL mice and patients.
Robin M, Andreu-Gallien J, Schlageter MH, Bengoufa D, Guillemot I, Pokorna K, Robert C, Larghero J, Rousselot P, Raffoux E, Dombret H, Fenaux P, Pla M, Charron D, Padua RA, Chomienne C. Robin M, et al. Among authors: pla m. Blood. 2006 Sep 15;108(6):1972-4. doi: 10.1182/blood-2006-03-013177. Epub 2006 May 25. Blood. 2006. PMID: 16728697 Free article.
PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia.
Padua RA, Larghero J, Robin M, le Pogam C, Schlageter MH, Muszlak S, Fric J, West R, Rousselot P, Phan TH, Mudde L, Teisserenc H, Carpentier AF, Kogan S, Degos L, Pla M, Bishop JM, Stevenson F, Charron D, Chomienne C. Padua RA, et al. Among authors: pla m. Nat Med. 2003 Nov;9(11):1413-7. doi: 10.1038/nm949. Epub 2003 Oct 19. Nat Med. 2003. PMID: 14566333
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
Gorombei P, Guidez F, Ganesan S, Chiquet M, Pellagatti A, Goursaud L, Tekin N, Beurlet S, Patel S, Guerenne L, Le Pogam C, Setterblad N, de la Grange P, LeBoeuf C, Janin A, Noguera ME, Sarda-Mantel L, Merlet P, Boultwood J, Konopleva M, Andreeff M, West R, Pla M, Adès L, Fenaux P, Krief P, Chomienne C, Omidvar N, Padua RA. Gorombei P, et al. Among authors: pla m. Int J Mol Sci. 2021 Sep 30;22(19):10658. doi: 10.3390/ijms221910658. Int J Mol Sci. 2021. PMID: 34638998 Free PMC article.
311 results