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The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop.
Ceridono M, Tellner P, Bauer D, Barroso J, Alépée N, Corvi R, De Smedt A, Fellows MD, Gibbs NK, Heisler E, Jacobs A, Jirova D, Jones D, Kandárová H, Kasper P, Akunda JK, Krul C, Learn D, Liebsch M, Lynch AM, Muster W, Nakamura K, Nash JF, Pfannenbecker U, Phillips G, Robles C, Rogiers V, Van De Water F, Liminga UW, Vohr HW, Wattrelos O, Woods J, Zuang V, Kreysa J, Wilcox P. Ceridono M, et al. Among authors: alepee n. Regul Toxicol Pharmacol. 2012 Aug;63(3):480-8. doi: 10.1016/j.yrtph.2012.06.001. Epub 2012 Jun 9. Regul Toxicol Pharmacol. 2012. PMID: 22687423
Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations.
Eskes C, Detappe V, Koëter H, Kreysa J, Liebsch M, Zuang V, Amcoff P, Barroso J, Cotovio J, Guest R, Hermann M, Hoffmann S, Masson P, Alépée N, Arce LA, Brüschweiler B, Catone T, Cihak R, Clouzeau J, D'Abrosca F, Delveaux C, Derouette JP, Engelking O, Facchini D, Fröhlicher M, Hofmann M, Hopf N, Molinari J, Oberli A, Ott M, Peter R, Sá-Rocha VM, Schenk D, Tomicic C, Vanparys P, Verdon B, Wallenhorst T, Winkler GC, Depallens O. Eskes C, et al. Among authors: alepee n. Regul Toxicol Pharmacol. 2012 Mar;62(2):393-403. doi: 10.1016/j.yrtph.2011.10.015. Epub 2011 Nov 6. Regul Toxicol Pharmacol. 2012. PMID: 22085589
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: skin sensitisation.
Goebel C, Aeby P, Ade N, Alépée N, Aptula A, Araki D, Dufour E, Gilmour N, Hibatallah J, Keller D, Kern P, Kirst A, Marrec-Fairley M, Maxwell G, Rowland J, Safford B, Schellauf F, Schepky A, Seaman C, Teichert T, Tessier N, Teissier S, Weltzien HU, Winkler P, Scheel J. Goebel C, et al. Among authors: alepee n. Regul Toxicol Pharmacol. 2012 Jun;63(1):40-52. doi: 10.1016/j.yrtph.2012.02.007. Epub 2012 Feb 21. Regul Toxicol Pharmacol. 2012. PMID: 22374415 Free article.
Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods.
Adriaens E, Barroso J, Eskes C, Hoffmann S, McNamee P, Alépée N, Bessou-Touya S, De Smedt A, De Wever B, Pfannenbecker U, Tailhardat M, Zuang V. Adriaens E, et al. Among authors: alepee n. Arch Toxicol. 2014 Mar;88(3):701-23. doi: 10.1007/s00204-013-1156-8. Epub 2013 Dec 28. Arch Toxicol. 2014. PMID: 24374802 Free PMC article.
Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD).
Barroso J, Pfannenbecker U, Adriaens E, Alépée N, Cluzel M, De Smedt A, Hibatallah J, Klaric M, Mewes KR, Millet M, Templier M, McNamee P. Barroso J, et al. Among authors: alepee n. Arch Toxicol. 2017 Feb;91(2):521-547. doi: 10.1007/s00204-016-1679-x. Epub 2016 Mar 21. Arch Toxicol. 2017. PMID: 26997338 Free PMC article. Review.
State-of-the-art and new options to assess T cell activation by skin sensitizers: Cosmetics Europe Workshop.
van Vliet E, Kühnl J, Goebel C, Martinozzi-Teissier S, Alépée N, Ashikaga T, Blömeke B, Del Bufalo A, Cluzel M, Corsini E, Delrue N, Desprez B, Gellatly N, Giese C, Gribaldo L, Hoffmann S, Klaric M, Maillere B, Naisbitt D, Pallardy M, Vocanson M, Petersohn D. van Vliet E, et al. Among authors: alepee n. ALTEX. 2018;35(2):179-192. doi: 10.14573/altex.1709011. Epub 2017 Oct 2. ALTEX. 2018. PMID: 28968481 Free article.
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, Harbell J, Hartung T, Kamp H, Varlet BL, Meloni M, McNamee P, Osborne R, Pape W, Pfannenbecker U, Prinsen M, Seaman C, Spielmann H, Stokes W, Trouba K, Berghe CV, Goethem FV, Vassallo M, Vinardell P, Zuang V. Scott L, et al. Among authors: alepee n. Toxicol In Vitro. 2010 Feb;24(1):1-9. doi: 10.1016/j.tiv.2009.05.019. Epub 2009 May 31. Toxicol In Vitro. 2010. PMID: 19490935 Review.
Skin sensitisation--moving forward with non-animal testing strategies for regulatory purposes in the EU.
Basketter D, Alépée N, Casati S, Crozier J, Eigler D, Griem P, Hubesch B, de Knecht J, Landsiedel R, Louekari K, Manou I, Maxwell G, Mehling A, Netzeva T, Petry T, Rossi LH. Basketter D, et al. Among authors: alepee n. Regul Toxicol Pharmacol. 2013 Dec;67(3):531-5. doi: 10.1016/j.yrtph.2013.10.002. Epub 2013 Oct 16. Regul Toxicol Pharmacol. 2013. PMID: 24140884
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.
Reisinger K, Hoffmann S, Alépée N, Ashikaga T, Barroso J, Elcombe C, Gellatly N, Galbiati V, Gibbs S, Groux H, Hibatallah J, Keller D, Kern P, Klaric M, Kolle S, Kuehnl J, Lambrechts N, Lindstedt M, Millet M, Martinozzi-Teissier S, Natsch A, Petersohn D, Pike I, Sakaguchi H, Schepky A, Tailhardat M, Templier M, van Vliet E, Maxwell G. Reisinger K, et al. Among authors: alepee n. Toxicol In Vitro. 2015 Feb;29(1):259-70. doi: 10.1016/j.tiv.2014.10.018. Toxicol In Vitro. 2015. PMID: 25448812 Free article.
85 results