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Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants.
Malki K, Uher R, Paya-Cano J, Binder E, Rietschel M, Zobel A, Mors O, Hauser J, Henigsberg N, Jerman B, Souery D, Placentino A, Ng MY, Cohen-Woods S, Sluyter F, Farmer A, Aitchison KJ, Craig IW, Lewis CM, McGuffin P, Schalkwyk LC. Malki K, et al. Biol Psychiatry. 2011 Feb 15;69(4):360-5. doi: 10.1016/j.biopsych.2010.08.011. Epub 2010 Oct 20. Biol Psychiatry. 2011. PMID: 20970119 Clinical Trial.
Genes and gene networks implicated in aggression related behaviour.
Malki K, Pain O, Du Rietz E, Tosto MG, Paya-Cano J, Sandnabba KN, de Boer S, Schalkwyk LC, Sluyter F. Malki K, et al. Neurogenetics. 2014 Oct;15(4):255-66. doi: 10.1007/s10048-014-0417-x. Epub 2014 Aug 22. Neurogenetics. 2014. PMID: 25142712
Combining clinical variables to optimize prediction of antidepressant treatment outcomes.
Iniesta R, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Stahl D, Dobson R, Aitchison KJ, Farmer A, Lewis CM, McGuffin P, Uher R. Iniesta R, et al. Among authors: malki k. J Psychiatr Res. 2016 Jul;78:94-102. doi: 10.1016/j.jpsychires.2016.03.016. Epub 2016 Apr 1. J Psychiatr Res. 2016. PMID: 27089522 Free article. Clinical Trial.
Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression.
Malki K, Tosto MG, Mouriño-Talín H, Rodríguez-Lorenzo S, Pain O, Jumhaboy I, Liu T, Parpas P, Newman S, Malykh A, Carboni L, Uher R, McGuffin P, Schalkwyk LC, Bryson K, Herbster M. Malki K, et al. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):235-250. doi: 10.1002/ajmg.b.32494. Epub 2016 Oct 1. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 27696737 Free PMC article.
112 results