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Transfer of IP₃ through gap junctions is critical, but not sufficient, for the spread of apoptosis.
Decrock E, Krysko DV, Vinken M, Kaczmarek A, Crispino G, Bol M, Wang N, De Bock M, De Vuyst E, Naus CC, Rogiers V, Vandenabeele P, Erneux C, Mammano F, Bultynck G, Leybaert L. Decrock E, et al. Among authors: bultynck g. Cell Death Differ. 2012 Jun;19(6):947-57. doi: 10.1038/cdd.2011.176. Epub 2011 Nov 25. Cell Death Differ. 2012. PMID: 22117194 Free PMC article.
TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis.
Rojas-Rivera D, Armisén R, Colombo A, Martínez G, Eguiguren AL, Díaz A, Kiviluoto S, Rodríguez D, Patron M, Rizzuto R, Bultynck G, Concha ML, Sierralta J, Stutzin A, Hetz C. Rojas-Rivera D, et al. Among authors: bultynck g. Cell Death Differ. 2012 Jun;19(6):1013-26. doi: 10.1038/cdd.2011.189. Epub 2012 Jan 13. Cell Death Differ. 2012. PMID: 22240901 Free PMC article.
IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.
Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G. Akl H, et al. Among authors: bultynck g. Cell Death Dis. 2013 May 16;4(5):e632. doi: 10.1038/cddis.2013.140. Cell Death Dis. 2013. PMID: 23681227 Free PMC article.
BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival.
Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A. Lisak D, et al. Among authors: bultynck g. Cell Death Differ. 2016 Feb;23(2):358-68. doi: 10.1038/cdd.2015.115. Epub 2015 Oct 16. Cell Death Differ. 2016. PMID: 26470731 Free PMC article.
Polycystins and cellular Ca2+ signaling.
Mekahli D, Parys JB, Bultynck G, Missiaen L, De Smedt H. Mekahli D, et al. Among authors: bultynck g. Cell Mol Life Sci. 2013 Aug;70(15):2697-712. doi: 10.1007/s00018-012-1188-x. Epub 2012 Oct 18. Cell Mol Life Sci. 2013. PMID: 23076254 Free PMC article. Review.
254 results