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Wiskott-Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice.
Nguyen DD, Wurbel MA, Goettel JA, Eston MA, Ahmed OS, Marin R, Boden EK, Villablanca EJ, Paidassi H, Ahuja V, Reinecker HC, Fiebiger E, Lacy-Hulbert A, Horwitz BH, Mora JR, Snapper SB. Nguyen DD, et al. Among authors: snapper sb. Gastroenterology. 2012 Sep;143(3):719-729.e2. doi: 10.1053/j.gastro.2012.06.008. Epub 2012 Jun 15. Gastroenterology. 2012. PMID: 22710191 Free PMC article.
Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.
Klein C, Nguyen D, Liu CH, Mizoguchi A, Bhan AK, Miki H, Takenawa T, Rosen FS, Alt FW, Mulligan RC, Snapper SB. Klein C, et al. Among authors: snapper sb. Blood. 2003 Mar 15;101(6):2159-66. doi: 10.1182/blood-2002-05-1423. Epub 2002 Nov 14. Blood. 2003. PMID: 12433691 Free article.
Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.
Cotta-de-Almeida V, Westerberg L, Maillard MH, Onaldi D, Wachtel H, Meelu P, Chung UI, Xavier R, Alt FW, Snapper SB. Cotta-de-Almeida V, et al. Among authors: snapper sb. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15424-9. doi: 10.1073/pnas.0706881104. Epub 2007 Sep 18. Proc Natl Acad Sci U S A. 2007. PMID: 17878299 Free PMC article.
248 results