Luijten M - Search Results

1

Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.

Schaap MM, Zwart EP, Wackers PF, Huijskens I, van de Water B, Breit TM, van Steeg H, Jonker MJ, Luijten M. Schaap MM, et al. Among authors: luijten m. Arch Toxicol. 2012 Nov;86(11):1717-27. doi: 10.1007/s00204-012-0883-6. Epub 2012 Jun 19. Arch Toxicol. 2012. PMID: 22710402

2

Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice.

Luijten M, Speksnijder EN, van Alphen N, Westerman A, Heisterkamp SH, van Benthem J, van Kreijl CF, Beems RB, van Steeg H. Luijten M, et al. Mutat Res. 2006 Apr 11;596(1-2):143-50. doi: 10.1016/j.mrfmmm.2005.12.011. Epub 2006 Feb 7. Mutat Res. 2006. PMID: 16464479

3

DNA repair-deficient Xpa/p53 knockout mice are sensitive to the non-genotoxic carcinogen cyclosporine A: escape of initiated cells from immunosurveillance?

van Kesteren PC, Beems RB, Luijten M, Robinson J, de Vries A, van Steeg H. van Kesteren PC, et al. Among authors: luijten m. Carcinogenesis. 2009 Mar;30(3):538-43. doi: 10.1093/carcin/bgp013. Epub 2009 Jan 9. Carcinogenesis. 2009. PMID: 19136475 Free PMC article.

4

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach.

Hernández LG, van Steeg H, Luijten M, van Benthem J. Hernández LG, et al. Among authors: luijten m. Mutat Res. 2009 Sep-Dec;682(2-3):94-109. doi: 10.1016/j.mrrev.2009.07.002. Epub 2009 Jul 22. Mutat Res. 2009. PMID: 19631282 Review.

5

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.

Jonker MJ, Bruning O, van Iterson M, Schaap MM, van der Hoeven TV, Vrieling H, Beems RB, de Vries A, van Steeg H, Breit TM, Luijten M. Jonker MJ, et al. Among authors: luijten m. Carcinogenesis. 2009 Oct;30(10):1805-12. doi: 10.1093/carcin/bgp190. Epub 2009 Aug 20. Carcinogenesis. 2009. PMID: 19696161

6

Transcriptomics analysis of retinoic acid embryotoxicity in rat postimplantation whole embryo culture.

Luijten M, van Beelen VA, Verhoef A, Renkens MF, van Herwijnen MH, Westerman A, van Schooten FJ, Pennings JL, Piersma AH. Luijten M, et al. Reprod Toxicol. 2010 Sep;30(2):333-40. doi: 10.1016/j.reprotox.2010.05.013. Epub 2010 May 19. Reprod Toxicol. 2010. PMID: 20488242

7

Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.

Robinson JF, van Beelen VA, Verhoef A, Renkens MF, Luijten M, van Herwijnen MH, Westerman A, Pennings JL, Piersma AH. Robinson JF, et al. Among authors: luijten m. Toxicol Sci. 2010 Dec;118(2):675-85. doi: 10.1093/toxsci/kfq292. Epub 2010 Sep 23. Toxicol Sci. 2010. PMID: 20864626

8

Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.

Kienhuis AS, Bessems JG, Pennings JL, Driessen M, Luijten M, van Delft JH, Peijnenburg AA, van der Ven LT. Kienhuis AS, et al. Among authors: luijten m. Toxicol Appl Pharmacol. 2011 Jan 15;250(2):96-107. doi: 10.1016/j.taap.2010.10.013. Epub 2010 Oct 21. Toxicol Appl Pharmacol. 2011. PMID: 20970440 Review.

9

Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis.

Yuan X, Jonker MJ, de Wilde J, Verhoef A, Wittink FR, van Benthem J, Bessems JG, Hakkert BC, Kuiper RV, van Steeg H, Breit TM, Luijten M. Yuan X, et al. Among authors: luijten m. J Appl Toxicol. 2011 Jul;31(5):421-30. doi: 10.1002/jat.1601. Epub 2010 Nov 9. J Appl Toxicol. 2011. PMID: 21061450

10

Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.

van Kesteren PC, Zwart PE, Pennings JL, Gottschalk WH, Kleinjans JC, van Delft JH, van Steeg H, Luijten M. van Kesteren PC, et al. Among authors: luijten m. Toxicol Sci. 2011 Sep;123(1):123-32. doi: 10.1093/toxsci/kfr169. Epub 2011 Jun 29. Toxicol Sci. 2011. PMID: 21715664

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