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Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface.
Schmidt MM, Townson SA, Andreucci AJ, King BM, Schirmer EB, Murillo AJ, Dombrowski C, Tisdale AW, Lowden PA, Masci AL, Kovalchin JT, Erbe DV, Wittrup KD, Furfine ES, Barnes TM. Schmidt MM, et al. Among authors: townson sa. Structure. 2013 Nov 5;21(11):1966-78. doi: 10.1016/j.str.2013.08.022. Epub 2013 Oct 10. Structure. 2013. PMID: 24120761 Free article.
Design of a superior cytokine antagonist for topical ophthalmic use.
Hou J, Townson SA, Kovalchin JT, Masci A, Kiner O, Shu Y, King BM, Schirmer E, Golden K, Thomas C, Garcia KC, Zarbis-Papastoitsis G, Furfine ES, Barnes TM. Hou J, et al. Among authors: townson sa. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3913-8. doi: 10.1073/pnas.1217996110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431173 Free PMC article.
Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface.
Shigdel UK, Lee SJ, Sowa ME, Bowman BR, Robison K, Zhou M, Pua KH, Stiles DT, Blodgett JAV, Udwary DW, Rajczewski AT, Mann AS, Mostafavi S, Hardy T, Arya S, Weng Z, Stewart M, Kenyon K, Morgenstern JP, Pan E, Gray DC, Pollock RM, Fry AM, Klausner RD, Townson SA, Verdine GL. Shigdel UK, et al. Among authors: townson sa. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17195-17203. doi: 10.1073/pnas.2006560117. Epub 2020 Jun 30. Proc Natl Acad Sci U S A. 2020. PMID: 32606248 Free PMC article.
14 results