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Administration of CD4+CD25highCD127- regulatory T cells preserves β-cell function in type 1 diabetes in children.
Marek-Trzonkowska N, Mysliwiec M, Dobyszuk A, Grabowska M, Techmanska I, Juscinska J, Wujtewicz MA, Witkowski P, Mlynarski W, Balcerska A, Mysliwska J, Trzonkowski P. Marek-Trzonkowska N, et al. Among authors: witkowski p. Diabetes Care. 2012 Sep;35(9):1817-20. doi: 10.2337/dc12-0038. Epub 2012 Jun 20. Diabetes Care. 2012. PMID: 22723342 Free PMC article. Clinical Trial.
Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes.
Marek-Trzonkowska N, Myśliwiec M, Iwaszkiewicz-Grześ D, Gliwiński M, Derkowska I, Żalińska M, Zieliński M, Grabowska M, Zielińska H, Piekarska K, Jaźwińska-Curyłło A, Owczuk R, Szadkowska A, Wyka K, Witkowski P, Młynarski W, Jarosz-Chobot P, Bossowski A, Siebert J, Trzonkowski P. Marek-Trzonkowska N, et al. Among authors: witkowski p. J Transl Med. 2016 Dec 1;14(1):332. doi: 10.1186/s12967-016-1090-7. J Transl Med. 2016. PMID: 27903296 Free PMC article. Clinical Trial.
Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up.
Marek-Trzonkowska N, Myśliwiec M, Dobyszuk A, Grabowska M, Derkowska I, Juścińska J, Owczuk R, Szadkowska A, Witkowski P, Młynarski W, Jarosz-Chobot P, Bossowski A, Siebert J, Trzonkowski P. Marek-Trzonkowska N, et al. Among authors: witkowski p. Clin Immunol. 2014 Jul;153(1):23-30. doi: 10.1016/j.clim.2014.03.016. Epub 2014 Apr 1. Clin Immunol. 2014. PMID: 24704576 Clinical Trial.
The time is crucial for ex vivo expansion of T regulatory cells for therapy.
Marek N, Bieniaszewska M, Krzystyniak A, Juścińska J, Myśliwska J, Witkowski P, Hellmann A, Trzonkowski P. Marek N, et al. Among authors: witkowski p. Cell Transplant. 2011;20(11-12):1747-58. doi: 10.3727/096368911X566217. Epub 2011 Apr 1. Cell Transplant. 2011. PMID: 21457615 Free article.
Islet cell transplant and the incorporation of Tregs.
Krzystyniak A, Gołąb K, Witkowski P, Trzonkowski P. Krzystyniak A, et al. Among authors: witkowski p. Curr Opin Organ Transplant. 2014 Dec;19(6):610-5. doi: 10.1097/MOT.0000000000000130. Curr Opin Organ Transplant. 2014. PMID: 25304813 Free PMC article. Review.
Utilization of leukapheresis and CD4 positive selection in Treg isolation and the ex-vivo expansion for a clinical application in transplantation and autoimmune disorders.
Gołąb K, Grose R, Trzonkowski P, Wickrema A, Tibudan M, Marek-Trzonkowska N, Matosz S, Solomina J, Ostrega D, Michael Millis J, Witkowski P. Gołąb K, et al. Among authors: witkowski p. Oncotarget. 2016 Nov 29;7(48):79474-79484. doi: 10.18632/oncotarget.13101. Oncotarget. 2016. PMID: 27821811 Free PMC article.
Cell banking for regulatory T cell-based therapy: strategies to overcome the impact of cryopreservation on the Treg viability and phenotype.
Gołąb K, Grose R, Placencia V, Wickrema A, Solomina J, Tibudan M, Konsur E, Ciepły K, Marek-Trzonkowska N, Trzonkowski P, Millis JM, Fung J, Witkowski P. Gołąb K, et al. Among authors: witkowski p. Oncotarget. 2018 Jan 3;9(11):9728-9740. doi: 10.18632/oncotarget.23887. eCollection 2018 Feb 9. Oncotarget. 2018. PMID: 29515766 Free PMC article.
Improved coating of pancreatic islets with regulatory T cells to create local immunosuppression by using the biotin-polyethylene glycol-succinimidyl valeric acid ester molecule.
Gołąb K, Kizilel S, Bal T, Hara M, Zielinski M, Grose R, Savari O, Wang XJ, Wang LJ, Tibudan M, Krzystyniak A, Marek-Trzonkowska N, Millis JM, Trzonkowski P, Witkowski P. Gołąb K, et al. Among authors: witkowski p. Transplant Proc. 2014 Jul-Aug;46(6):1967-71. doi: 10.1016/j.transproceed.2014.05.075. Transplant Proc. 2014. PMID: 25131084 Free PMC article.
184 results