Arita T - Search Results

1

Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPARγ modulators.

Furukawa A, Arita T, Fukuzaki T, Mori M, Honda T, Satoh S, Matsui Y, Wakabayashi K, Hayashi S, Nakamura K, Araki K, Kuroha M, Tanaka J, Wakimoto S, Suzuki O, Ohsumi J. Furukawa A, et al. Among authors: arita t. Eur J Med Chem. 2012 Aug;54:522-33. doi: 10.1016/j.ejmech.2012.05.040. Epub 2012 Jun 7. Eur J Med Chem. 2012. PMID: 22727448

2

(-)-Cercosporamide derivatives as novel antihyperglycemic agents.

Furukawa A, Arita T, Satoh S, Araki K, Kuroha M, Ohsumi J. Furukawa A, et al. Among authors: arita t. Bioorg Med Chem Lett. 2009 Feb 1;19(3):724-6. doi: 10.1016/j.bmcl.2008.12.035. Epub 2008 Dec 11. Bioorg Med Chem Lett. 2009. PMID: 19109017

3

Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives.

Furukawa A, Arita T, Satoh S, Wakabayashi K, Hayashi S, Matsui Y, Araki K, Kuroha M, Ohsumi J. Furukawa A, et al. Among authors: arita t. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2095-8. doi: 10.1016/j.bmcl.2010.02.073. Epub 2010 Feb 20. Bioorg Med Chem Lett. 2010. PMID: 20219371

4

Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARγ partial agonists.

Furukawa A, Arita T, Fukuzaki T, Satoh S, Mori M, Honda T, Matsui Y, Wakabayashi K, Hayashi S, Araki K, Ohsumi J. Furukawa A, et al. Among authors: arita t. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1348-51. doi: 10.1016/j.bmcl.2011.12.066. Epub 2011 Dec 16. Bioorg Med Chem Lett. 2012. PMID: 22225641

5

Synthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach.

Matsufuji T, Shimada K, Kobayashi S, Ichikawa M, Kawamura A, Fujimoto T, Arita T, Hara T, Konishi M, Abe-Ohya R, Izumi M, Sogawa Y, Nagai Y, Yoshida K, Abe Y, Kimura T, Takahashi H. Matsufuji T, et al. Among authors: arita t. Bioorg Med Chem. 2015 Jan 1;23(1):89-104. doi: 10.1016/j.bmc.2014.11.018. Epub 2014 Nov 21. Bioorg Med Chem. 2015. PMID: 25497965

6

Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity.

Arita T, Asano M, Kubota K, Domon Y, Machinaga N, Shimada K. Arita T, et al. Bioorg Med Chem Lett. 2019 Dec 1;29(23):126748. doi: 10.1016/j.bmcl.2019.126748. Epub 2019 Oct 19. Bioorg Med Chem Lett. 2019. PMID: 31676224

7

Discovery of novel chiral diazepines as bombesin receptor subtype-3 (BRS-3) agonists with low brain penetration.

Matsufuji T, Shimada K, Kobayashi S, Kawamura A, Fujimoto T, Arita T, Hara T, Konishi M, Abe-Ohya R, Izumi M, Sogawa Y, Nagai Y, Yoshida K, Takahashi H. Matsufuji T, et al. Among authors: arita t. Bioorg Med Chem Lett. 2014 Feb 1;24(3):750-5. doi: 10.1016/j.bmcl.2013.12.106. Epub 2014 Jan 2. Bioorg Med Chem Lett. 2014. PMID: 24412111

8

Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity.

Arita T, Asano M, Kubota K, Domon Y, Machinaga N, Shimada K. Arita T, et al. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1938-1942. doi: 10.1016/j.bmcl.2019.05.045. Epub 2019 May 21. Bioorg Med Chem Lett. 2019. PMID: 31147104

9

Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity.

Arita T, Asano M, Kubota K, Domon Y, Machinaga N, Shimada K. Arita T, et al. Bioorg Med Chem. 2020 Nov 1;28(21):115714. doi: 10.1016/j.bmc.2020.115714. Epub 2020 Aug 18. Bioorg Med Chem. 2020. PMID: 33065431

10

Jejunal interposition to prevent postgastrectomy syndromes.

Morii Y, Arita T, Shimoda K, Yasuda K, Matsui Y, Inomata M, Kitano S. Morii Y, et al. Among authors: arita t. Br J Surg. 2000 Nov;87(11):1576-9. doi: 10.1046/j.1365-2168.2000.01555.x. Br J Surg. 2000. PMID: 11091248

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