Appeldoorn CC - Search Results

1

Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation.

Gaillard PJ, Appeldoorn CC, Rip J, Dorland R, van der Pol SM, Kooij G, de Vries HE, Reijerkerk A. Gaillard PJ, et al. Among authors: appeldoorn cc. J Control Release. 2012 Dec 28;164(3):364-9. doi: 10.1016/j.jconrel.2012.06.022. Epub 2012 Jun 23. J Control Release. 2012. PMID: 22732475

2

Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats.

Rip J, Chen L, Hartman R, van den Heuvel A, Reijerkerk A, van Kregten J, van der Boom B, Appeldoorn C, de Boer M, Maussang D, de Lange EC, Gaillard PJ. Rip J, et al. J Drug Target. 2014 Jun;22(5):460-7. doi: 10.3109/1061186X.2014.888070. Epub 2014 Feb 14. J Drug Target. 2014. PMID: 24524555 Free PMC article.

3

Glutathione pegylated liposomal methylprednisolone administration after the early phase of status epilepticus did not modify epileptogenesis in the rat.

Holtman L, van Vliet EA, Appeldoorn C, Gaillard PJ, de Boer M, Dorland R, Wadman WJ, Gorter JA. Holtman L, et al. Epilepsy Res. 2014 Mar;108(3):396-404. doi: 10.1016/j.eplepsyres.2014.01.010. Epub 2014 Jan 31. Epilepsy Res. 2014. PMID: 24556423

4

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

Gaillard PJ, Appeldoorn CC, Dorland R, van Kregten J, Manca F, Vugts DJ, Windhorst B, van Dongen GA, de Vries HE, Maussang D, van Tellingen O. Gaillard PJ, et al. Among authors: appeldoorn cc. PLoS One. 2014 Jan 8;9(1):e82331. doi: 10.1371/journal.pone.0082331. eCollection 2014. PLoS One. 2014. PMID: 24416140 Free PMC article.

5

Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation.

Reijerkerk A, Appeldoorn CC, Rip J, de Boer M, Gaillard PJ. Reijerkerk A, et al. Among authors: appeldoorn cc. Invest Ophthalmol Vis Sci. 2014 Apr 28;55(4):2788-94. doi: 10.1167/iovs.13-13599. Invest Ophthalmol Vis Sci. 2014. PMID: 24692123

6

Glutathione PEGylated liposomal methylprednisolone (2B3-201) attenuates CNS inflammation and degeneration in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis.

Lee DH, Rötger C, Appeldoorn CC, Reijerkerk A, Gladdines W, Gaillard PJ, Linker RA. Lee DH, et al. Among authors: appeldoorn cc. J Neuroimmunol. 2014 Sep 15;274(1-2):96-101. doi: 10.1016/j.jneuroim.2014.06.025. Epub 2014 Jul 6. J Neuroimmunol. 2014. PMID: 25037177

7

Targeted blood-to-brain drug delivery --10 key development criteria.

Gaillard PJ, Visser CC, Appeldoorn CC, Rip J. Gaillard PJ, et al. Among authors: appeldoorn cc. Curr Pharm Biotechnol. 2012 Sep;13(12):2328-39. doi: 10.2174/138920112803341815. Curr Pharm Biotechnol. 2012. PMID: 23016639 Review.

8

CNS-targeted glucocorticoid reduces pathology in mouse model of amyotrophic lateral sclerosis.

Evans MC, Gaillard PJ, de Boer M, Appeldoorn C, Dorland R, Sibson NR, Turner MR, Anthony DC, Stolp HB. Evans MC, et al. Acta Neuropathol Commun. 2014 Jun 13;2:66. doi: 10.1186/2051-5960-2-66. Acta Neuropathol Commun. 2014. PMID: 24923195 Free PMC article.

9

Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma.

Höbel S, Appeldoorn CC, Gaillard PJ, Aigner A. Höbel S, et al. Among authors: appeldoorn cc. Pharmaceuticals (Basel). 2011 Dec 16;4(12):1591-1606. doi: 10.3390/ph4121591. Pharmaceuticals (Basel). 2011. PMID: 27721338 Free PMC article.

10

Blocking endothelial adhesion molecules: a potential therapeutic strategy to combat atherogenesis.

Lutters BC, Leeuwenburgh MA, Appeldoorn CC, Molenaar TJ, Van Berkel TJ, Biessen EA. Lutters BC, et al. Among authors: appeldoorn cc. Curr Opin Lipidol. 2004 Oct;15(5):545-52. doi: 10.1097/00041433-200410000-00008. Curr Opin Lipidol. 2004. PMID: 15361790 Review.

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