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Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis.
Gande R, Gibson KJ, Brown AK, Krumbach K, Dover LG, Sahm H, Shioyama S, Oikawa T, Besra GS, Eggeling L. Gande R, et al. Among authors: besra gs. J Biol Chem. 2004 Oct 22;279(43):44847-57. doi: 10.1074/jbc.M408648200. Epub 2004 Aug 11. J Biol Chem. 2004. PMID: 15308633 Free article.
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core.
Alderwick LJ, Radmacher E, Seidel M, Gande R, Hitchen PG, Morris HR, Dell A, Sahm H, Eggeling L, Besra GS. Alderwick LJ, et al. Among authors: besra gs. J Biol Chem. 2005 Sep 16;280(37):32362-71. doi: 10.1074/jbc.M506339200. Epub 2005 Jul 21. J Biol Chem. 2005. PMID: 16040600 Free article.
507 results