Arnold FH - Search Results

1

SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis.

Romero PA, Stone E, Lamb C, Chantranupong L, Krause A, Miklos AE, Hughes RA, Fechtel B, Ellington AD, Arnold FH, Georgiou G. Romero PA, et al. Among authors: arnold fh. ACS Synth Biol. 2012 Jun 15;1(6):221-8. doi: 10.1021/sb300014t. ACS Synth Biol. 2012. PMID: 22737599 Free PMC article.

2

General method for sequence-independent site-directed chimeragenesis.

Hiraga K, Arnold FH. Hiraga K, et al. Among authors: arnold fh. J Mol Biol. 2003 Jul 4;330(2):287-96. doi: 10.1016/s0022-2836(03)00590-4. J Mol Biol. 2003. PMID: 12823968

3

Library analysis of SCHEMA-guided protein recombination.

Meyer MM, Silberg JJ, Voigt CA, Endelman JB, Mayo SL, Wang ZG, Arnold FH. Meyer MM, et al. Among authors: arnold fh. Protein Sci. 2003 Aug;12(8):1686-93. doi: 10.1110/ps.0306603. Protein Sci. 2003. PMID: 12876318 Free PMC article.

4

Functional evolution and structural conservation in chimeric cytochromes p450: calibrating a structure-guided approach.

Otey CR, Silberg JJ, Voigt CA, Endelman JB, Bandara G, Arnold FH. Otey CR, et al. Among authors: arnold fh. Chem Biol. 2004 Mar;11(3):309-18. doi: 10.1016/j.chembiol.2004.02.018. Chem Biol. 2004. PMID: 15123260

5

SCHEMA-guided protein recombination.

Silberg JJ, Endelman JB, Arnold FH. Silberg JJ, et al. Among authors: arnold fh. Methods Enzymol. 2004;388:35-42. doi: 10.1016/S0076-6879(04)88004-2. Methods Enzymol. 2004. PMID: 15289059 No abstract available.

6

Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins.

Drummond DA, Iverson BL, Georgiou G, Arnold FH. Drummond DA, et al. Among authors: arnold fh. J Mol Biol. 2005 Jul 22;350(4):806-16. doi: 10.1016/j.jmb.2005.05.023. J Mol Biol. 2005. PMID: 15939434

7

Structure-guided SCHEMA recombination of distantly related beta-lactamases.

Meyer MM, Hochrein L, Arnold FH. Meyer MM, et al. Among authors: arnold fh. Protein Eng Des Sel. 2006 Dec;19(12):563-70. doi: 10.1093/protein/gzl045. Epub 2006 Nov 6. Protein Eng Des Sel. 2006. PMID: 17090554

8

Diversification of catalytic function in a synthetic family of chimeric cytochrome p450s.

Landwehr M, Carbone M, Otey CR, Li Y, Arnold FH. Landwehr M, et al. Among authors: arnold fh. Chem Biol. 2007 Mar;14(3):269-78. doi: 10.1016/j.chembiol.2007.01.009. Chem Biol. 2007. PMID: 17379142 Free PMC article.

9

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution.

Bloom JD, Romero PA, Lu Z, Arnold FH. Bloom JD, et al. Among authors: arnold fh. Biol Direct. 2007 Jun 28;2:17. doi: 10.1186/1745-6150-2-17. Biol Direct. 2007. PMID: 17598905 Free PMC article.

10

A family of thermostable fungal cellulases created by structure-guided recombination.

Heinzelman P, Snow CD, Wu I, Nguyen C, Villalobos A, Govindarajan S, Minshull J, Arnold FH. Heinzelman P, et al. Among authors: arnold fh. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5610-5. doi: 10.1073/pnas.0901417106. Epub 2009 Mar 23. Proc Natl Acad Sci U S A. 2009. PMID: 19307582 Free PMC article.

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